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山楂黄酮对微波辐射大鼠肾脏损伤的治疗作用

胡琦 王海燕 陈泊宇 李晓宇 唐玉 张林弟 郑雪微 高晓宁 罗军

吉林医药学院学报2016,Vol.37Issue(3):175-177,3.
吉林医药学院学报2016,Vol.37Issue(3):175-177,3.

山楂黄酮对微波辐射大鼠肾脏损伤的治疗作用

The effect of hawthorn flavones on kidney damage of microwave radiation rats

胡琦 1王海燕 1陈泊宇 1李晓宇 1唐玉 1张林弟 1郑雪微 1高晓宁 1罗军2

作者信息

  • 1. 吉林医药学院口腔影像系,吉林吉林 132013
  • 2. 吉林医药学院生化教研室,吉林吉林 132013
  • 折叠

摘要

Abstract

Objective To inquire into the effect of hawthorn flavones on kidney tissue exposured to microwave radia-tion in rats.Methods 50 Wistar rats were randomly divided into control group,the radiation model group,the low dose group 40 mg/kg· d)),the middle dose group 60 mg/kg· d)) and the high dose group 80 mg/kg· d) ) .Hawthorn flavones were given to the radiation model group which received 200 mW/cm2 radiation for 7 consecu-tive days,one day was 6 mins.Then the rats were sacrificed.Testicular cells morphological changes were observed.The rat kidney tissue's superoxide dismutase,T-SOD,MDA were measured.Results To compare with the radiation model group,the hawthorn flavones group'kidney tissue damage were improved.The kidney tubules and its epithelial cells ar-range were regularly,the cell borders were recognizable,the cytoplasm were light shining,the nuclear swelling and the hyperemia phenomenon was eased obviously.The content of MDA was decreased obviously P<0.01) ,while the con-tent of T-SOD increased P<0.05).Conclusion Rats kidney tissue damage could be caused by 200 W/cm2 micro-wave exposures and the hawthorn flavones has certain treatment on it.

关键词

山楂黄酮/微波辐射/肾脏损伤

Key words

hawthorn flavanone/microwave radiation/kidney damage

分类

医药卫生

引用本文复制引用

胡琦,王海燕,陈泊宇,李晓宇,唐玉,张林弟,郑雪微,高晓宁,罗军..山楂黄酮对微波辐射大鼠肾脏损伤的治疗作用[J].吉林医药学院学报,2016,37(3):175-177,3.

基金项目

吉林省教育厅“十二五”科学技术研究项目2012488);吉林省大学生创新创业项目. ()

吉林医药学院学报

1673-2995

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