吉林医药学院学报2016,Vol.37Issue(3):175-177,3.
山楂黄酮对微波辐射大鼠肾脏损伤的治疗作用
The effect of hawthorn flavones on kidney damage of microwave radiation rats
摘要
Abstract
Objective To inquire into the effect of hawthorn flavones on kidney tissue exposured to microwave radia-tion in rats.Methods 50 Wistar rats were randomly divided into control group,the radiation model group,the low dose group 40 mg/kg· d)),the middle dose group 60 mg/kg· d)) and the high dose group 80 mg/kg· d) ) .Hawthorn flavones were given to the radiation model group which received 200 mW/cm2 radiation for 7 consecu-tive days,one day was 6 mins.Then the rats were sacrificed.Testicular cells morphological changes were observed.The rat kidney tissue's superoxide dismutase,T-SOD,MDA were measured.Results To compare with the radiation model group,the hawthorn flavones group'kidney tissue damage were improved.The kidney tubules and its epithelial cells ar-range were regularly,the cell borders were recognizable,the cytoplasm were light shining,the nuclear swelling and the hyperemia phenomenon was eased obviously.The content of MDA was decreased obviously P<0.01) ,while the con-tent of T-SOD increased P<0.05).Conclusion Rats kidney tissue damage could be caused by 200 W/cm2 micro-wave exposures and the hawthorn flavones has certain treatment on it.关键词
山楂黄酮/微波辐射/肾脏损伤Key words
hawthorn flavanone/microwave radiation/kidney damage分类
医药卫生引用本文复制引用
胡琦,王海燕,陈泊宇,李晓宇,唐玉,张林弟,郑雪微,高晓宁,罗军..山楂黄酮对微波辐射大鼠肾脏损伤的治疗作用[J].吉林医药学院学报,2016,37(3):175-177,3.基金项目
吉林省教育厅“十二五”科学技术研究项目2012488);吉林省大学生创新创业项目. ()