口腔疾病防治2016，Vol.24Issue(5)：267-272,6.DOI:10.12016/j.issn.2096-1456.2016.05.002
钛种植体表面早期成骨方式的动物模型研究
Study on animal model of early osteogenesis on the surface of titanium implant
摘要
Abstract
Objective To study the animal model suitable for the observation of early osteogenesis on the surface of ti-tanium implant. Methods Modify implants mode which the outer thread of the implant next to the osteotomy bone wall while the inter thread keep a certain distance to osteotomy bone wall was adopted in the 1-year-old male Beagle dogs. After extraction of all mandibular premolars and first molar bilaterally in the 4 dogs, 20 implants replaced the position. All sec-tions were stained for histological analysis. Results The surgical wound in the 4 dogs healed by first intention. The tita-nium implants have good stability. The formation of the new bone, which include the contact osteogenesis and distance osteogenesis, was observed as it progressed not only in the surface of the osteotomy bone wall but also in the surface of the implants. Conclusion The established animal model is suitable for the observation of both early osteogenesis in implant and the influences of implant surface properties to the early osteogenesis.关键词
早期成骨/接触成骨/距离成骨/动物模型/Beagle犬Key words
Early osteogenesis/Contact osteogenesis/Distance osteogenesis/Animal model/Beagle dogs分类
医药卫生引用本文复制引用
赖春花,周磊,贾芳,丁祥龙,吴静漪,高岩,林曦..钛种植体表面早期成骨方式的动物模型研究[J].口腔疾病防治,2016,24(5):267-272,6.基金项目
国家自然科学基金(81170998) （81170998）
广东省医学科研基金(C2012034) （C2012034）
