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牙龈卟啉单胞菌及其牙龈蛋白酶K对青少年牙龈健康的影响

韩志强 柏扬 肖水清 孙菲 何萍

国际口腔医学杂志2016,Vol.43Issue(3):283-287,5.
国际口腔医学杂志2016,Vol.43Issue(3):283-287,5.DOI:10.7518/gjkq.2016.03.007

牙龈卟啉单胞菌及其牙龈蛋白酶K对青少年牙龈健康的影响

Influence ofPorphyromonas gingivalis and its gingipain K in healthy gingiva of teenagers

韩志强 1柏扬 2肖水清 1孙菲 3何萍1

作者信息

  • 1. 济南市口腔医院 济南 250001
  • 2. 济南市第一人民医院口腔科 济南 250000
  • 3. 滨州医学院口腔医学院正畸教研室 滨州 256603
  • 折叠

摘要

Abstract

Objective To explore the relationship of Porphyromonas gingivalis(P. gingivalis), gingipain K(Kgp) and puberty gingivitis in the subgingival. Methods Subjects(12- to 17-year-old children) included 50, 25, and 32 periodontally healthy, puberty gingivitis indexⅠ, and puberty gingivitis index Ⅱ children, respectively. 16S rDNA PCR was conducted to detect P. gingivalis and Kgp from the samples. Chi-square test was performed to compare the prevalence of Kgp and P. gingivalis in the three groups. Spearman correlation analysis was also employed to evaluate the relationship between the relative quantity of Kgp and periodontal parameters. Results P. gingivalis in the puberty gingivitis index Ⅱ group was higher than that in the periodontally healthy group. Puberty gingivitis index Ⅱ was higher than puberty gingivitis index Ⅰ and periodontally healthy groups. Puberty gingivitis index Ⅱ, puberty gingivitis index Ⅱ, and periodontally healthy groups were significantly different from one another(P<0.01). Puberty gingivitis index Ⅰ was also significantly different from puberty gingivitis index Ⅱ(P<0.05). Kgp in the puberty gingivitis index Ⅰ group is higher than that in the periodontally healthy group(P<0.01). Puberty gingivitis index Ⅱ is higher than puberty gingivitis index Ⅰ and periodontally healthy groups. Puberty gingivitis index Ⅰ(P<0.05) and puberty gingivitis index Ⅱ(P<0.01) are significantly different from the periodontally healthy group. P. gingivalis and Kgp detection rates increased in the gingivitis index. Conclusion Kgp and P. gingivalis areclosely related to puberty gingivitis in the subgingival.

关键词

青少年/牙龈卟啉单胞菌/牙龈蛋白酶K/牙龈炎

Key words

teenagers/Porphyromonas gingivalis/gingipain K/gingivitis

分类

医药卫生

引用本文复制引用

韩志强,柏扬,肖水清,孙菲,何萍..牙龈卟啉单胞菌及其牙龈蛋白酶K对青少年牙龈健康的影响[J].国际口腔医学杂志,2016,43(3):283-287,5.

国际口腔医学杂志

OA北大核心CSCDCSTPCD

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