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低龄儿童龋微生物群落的研究进展

黄慧 张琼 邹静

国际口腔医学杂志2016,Vol.43Issue(3):295-297,3.
国际口腔医学杂志2016,Vol.43Issue(3):295-297,3.DOI:10.7518/gjkq.2016.03.010

低龄儿童龋微生物群落的研究进展

Research progress on oral microbiota of early childhood caries

黄慧 1张琼 1邹静1

作者信息

  • 1. 口腔疾病研究国家重点实验室 华西口腔医院儿童口腔科 四川大学 成都 610041
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摘要

Abstract

Not only several selected bacteria but also oral microbiota are closely related to the initiation and progression of early childhood caries(ECC). Oral microbes and the host are in a dynamic balance in normal physiological conditions; however, this varying balance ultimately determines oral infectious disease. Microbiota varies between individual, plaque, and saliva. The microbial diversity of caries-free children is higher than that of severe ECC(SECC) children, and it decreases before caries appears, that is, the caries may be associated with the decrease of microbial diversity. Microbiota composition of SECC children significantly changes post-therapy. Probiotics can decrease the number of cariogenic bacteria and prevalence rate of caries. Learning more about children’s oral microbiota will provide higher predictability of ECC development and lead to the implementation of targeted early intervention. This review focuses on recent microbiological findings about ECC-associated microbiota.

关键词

低龄儿童龋/微生态/口腔微生物群

Key words

early childhood caries/microecology/oral microbiota

分类

医药卫生

引用本文复制引用

黄慧,张琼,邹静..低龄儿童龋微生物群落的研究进展[J].国际口腔医学杂志,2016,43(3):295-297,3.

国际口腔医学杂志

OA北大核心CSCDCSTPCD

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