国际口腔医学杂志2016，Vol.43Issue(3)：329-332,4.DOI:10.7518/gjkq.2016.03.017
低强度脉冲超声在牙周组织再生中的作用
Effects of low-intensity pulsed ultrasound in periodontal tissue regeneration
李紫嫣 1李鑫 1周进茹 1李磊1
作者信息
- 1. 口腔疾病研究国家重点实验室 华西口腔医院修复科 四川大学 成都 610041
- 折叠
摘要
Abstract
Periodontal disease, root caries, maxillofacial deformity, and trauma will cause defects in periodontal supporting tissue, such as alveolar bone, gingiva, and periodontium. Low-intensity pulsed ultrasound(LIPUS) can generate hyperthermia and mechanical stimulation, which can promote the generation and differentiation of cementoblast, odontoblast, and periodontal ligament cell(PDLC). PDLC can differentiate into mesodermal lineages and subsequently generate alveolar bone, cementum, and periodontium. Alkaline phosphatase(AKP) and osteocalcin(OCN) are the advanced markers of osteogenesis and osteogenic differentiation. LIPUS-stimulated PDLC shows improved AKP activity and OCN expression. LIPUS can also decrease the root absorption during orthodontic treatment; accelerate the proliferation, differentiation, and mineralization of cementoblast, which can repair root defects; and improve the expression of connective tissue growth factor that can accelerate angiogenesis and healing of periodontal tissue. LIPUS, as a safe and non-invasive treatment, can be applied in periodontal tissue regeneration. However, further research should be conducted to determine the most suitable stimulation intensity and treatment time.关键词
低强度脉冲超声/牙周组织/再生Key words
low-intensity pulsed ultrasound/periodontium/regeneration分类
医药卫生引用本文复制引用
李紫嫣,李鑫,周进茹,李磊..低强度脉冲超声在牙周组织再生中的作用[J].国际口腔医学杂志,2016,43(3):329-332,4.
