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血红素加氧酶-1的抗肿瘤细胞凋亡作用研究进展

巫亚龙(综述) 唐圣松(审校)

临床与病理杂志2016,Vol.36Issue(4):496-500,5.
临床与病理杂志2016,Vol.36Issue(4):496-500,5.DOI:10.3978/j.issn.2095-6959.2016.04.029

血红素加氧酶-1的抗肿瘤细胞凋亡作用研究进展

Advances in apoptosis of heme oxygenase-1 anti-tumor cell

巫亚龙(综述) 1唐圣松(审校)1

作者信息

  • 1. 南华大学药物药理研究所,湖南 衡阳 421001
  • 折叠

摘要

Abstract

Heme oxygenase-1 (HO-1) is a kind of antioxidative enzymes which is the rate-limiting enzyme of heme degradation and produces biliru-bin, carbon monoxide (CO), and iron. HO-1 plays a variety of biological functions in the body, its protective mechanism relates undoubtedly to various kinds of metabolites produced in catabolism, but the exact mechanism remains unknown. With the deepening of the study, the correlation between HO-1 and tumor gradually increased, indicating that the tumor closely involved in the regulation of tumor cell proliferation and other processes. hTis article is a review mainly on the apoptosis of HO-1.

关键词

血红素加氧酶-1/肿瘤/细胞凋亡

Key words

heme oxygenase-1/neoplasms/apoptosis

引用本文复制引用

巫亚龙(综述),唐圣松(审校)..血红素加氧酶-1的抗肿瘤细胞凋亡作用研究进展[J].临床与病理杂志,2016,36(4):496-500,5.

基金项目

湖南省高校科技创新平台开放基金(09K072,12K120)。hTis work was supported by Open Fund of Science and Technology Innovation Platform in Hunan Province (09K072,12K120), P. R. China (09K072,12K120)

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