高校化学工程学报2016,Vol.30Issue(2):454-458,5.DOI:10.3969/j.issn.1003-9015.2016.02.029
pH敏感微球及其在酸性水中的控制释放性能
pH-Sensitive Microspheres and its Controlled Release Performance in Acidic Aqueous Solutions
摘要
Abstract
K2HPO4 entrapped pH-sensitive polymeric Eudragit E100 (EPO) microspheres were prepared by spray drying method. Magnesium stearate was added as another carrier material to improve hardness and release performance. The release rate of alkaline K2HPO4 is controlled by environmental pH changes, which makes the microsphere suitable for pH adjustment of acidic waste water. The effects of microsphere composition and preparation procedure on microsphere size and morphology were investigated. The optimal conditions are found as: 35/65 (W/W) of EPO/magnesium stearate, 120℃ injection temperature, 3% injection concentration and 5 mL⋅min−1 injection volume. The pH adjustment ability of the microspheres in pH = 3 acidic water was examined, and the results show that the pH value increases to 6.8 within 1 h and then decreases to 5 after 4 h. The pH remained unchanged in a long time.关键词
pH敏感微球/Eudragit E100/酸性废水/喷雾干燥法/控制释放Key words
pH-sensitive microspheres/Eudragit E100/acidic waste water/spray drying method/control release分类
化学化工引用本文复制引用
陈全,姚娜,钟曼丽,孙清清,章莉娟..pH敏感微球及其在酸性水中的控制释放性能[J].高校化学工程学报,2016,30(2):454-458,5.基金项目
国家自然科学基金(91434125);中央高校自主科研项目(2014ZP0050)。 (91434125)