海洋科学2016,Vol.40Issue(1):147-154,8.DOI:10.11759/hykx20150115001
水产动物雷帕霉素受体信号通路的研究进展
Mechanistic target of rapamycin signaling in aquatic animals
摘要
Abstract
mTOR signaling is widely present in eukaryotic cells. It can receive signals from nutrients, growth fac-tors, or environmental stresses and precisely regulate the growth and physiological activity of cells via monitoring anabolism and catabolism. Studies on mTOR signaling in aquatic animals have been performed only in fish, shrimps, and crabs and are far behind the studies on model organisms. In this article, we overviewed the research progress of mTOR signaling in recent years, including the discovery and components of TOR, the factors involved in mTOR signaling, and the regulation mechanism of mTOR signaling in the progression of life. This article also focuses on the current researches and the necessity of studying the mTOR signaling pathway in aquatic animals. This could provide a reference for further researches on the mTOR signaling pathway in aquatic animals.关键词
mTOR/雷帕霉素/水产动物/代谢调控Key words
mTOR/rapamycin/aquatic animals/metabolism regulation分类
生物科学引用本文复制引用
辛芳,王雷,刘梅,王宝杰,蒋克勇,孙国琼..水产动物雷帕霉素受体信号通路的研究进展[J].海洋科学,2016,40(1):147-154,8.基金项目
国家自然科学基金项目(41406151)@@@@Program of National Natural Science Funds of China (41406151) (41406151)