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水产动物雷帕霉素受体信号通路的研究进展

辛芳 王雷 刘梅 王宝杰 蒋克勇 孙国琼

海洋科学2016,Vol.40Issue(1):147-154,8.
海洋科学2016,Vol.40Issue(1):147-154,8.DOI:10.11759/hykx20150115001

水产动物雷帕霉素受体信号通路的研究进展

Mechanistic target of rapamycin signaling in aquatic animals

辛芳 1王雷 2刘梅 1王宝杰 1蒋克勇 1孙国琼1

作者信息

  • 1. 中国科学院 海洋研究所,中国科学院 实验海洋生物学重点实验室,青岛海洋科学与技术国家实验室 海洋生物学与生物技术功能实验室,山东青岛 266071
  • 2. 中国科学院大学,北京 100049
  • 折叠

摘要

Abstract

mTOR signaling is widely present in eukaryotic cells. It can receive signals from nutrients, growth fac-tors, or environmental stresses and precisely regulate the growth and physiological activity of cells via monitoring anabolism and catabolism. Studies on mTOR signaling in aquatic animals have been performed only in fish, shrimps, and crabs and are far behind the studies on model organisms. In this article, we overviewed the research progress of mTOR signaling in recent years, including the discovery and components of TOR, the factors involved in mTOR signaling, and the regulation mechanism of mTOR signaling in the progression of life. This article also focuses on the current researches and the necessity of studying the mTOR signaling pathway in aquatic animals. This could provide a reference for further researches on the mTOR signaling pathway in aquatic animals.

关键词

mTOR/雷帕霉素/水产动物/代谢调控

Key words

mTOR/rapamycin/aquatic animals/metabolism regulation

分类

生物科学

引用本文复制引用

辛芳,王雷,刘梅,王宝杰,蒋克勇,孙国琼..水产动物雷帕霉素受体信号通路的研究进展[J].海洋科学,2016,40(1):147-154,8.

基金项目

国家自然科学基金项目(41406151)@@@@Program of National Natural Science Funds of China (41406151) (41406151)

海洋科学

OA北大核心CSCDCSTPCD

1000-3096

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