检验医学与临床2016，Vol.13Issue(9)：1177-1178,1183,3.DOI:10.3969/j.issn.1672-9455.2016.09.010
急性缺血性脑卒中 Lp-PLA2水平与新 TOAST 分型关系的探究
Lp-PLA2 level in patients with acute ischemic stroke and its relationship with new-TOAST subtypes
摘要
Abstract
Objective To investigate the changes of serum lipoprotein associated phospholipase A2 in patients with acute ischemic stroke and explore the relationship between Lp‐PLA2 and the new‐TOAST subtype .Methods Totally 159 patients with acute ischemic stroke and 100 healthy persons were selected from the Hebei Provice People′s Hospital from 2014 to 2015 .The concentration changes of serum Lp‐PLA2 were measured and the relation‐ship between Lp‐PLA2 and TOAST subtypes were analyzed .Results Levels of Lp‐PLA2 increased significantly in a‐cute ischemic stroke patients than those in the controls(P<0 .05) and levels of Lp‐PLA2 in AT group was the high‐est(P<0 .05) .Logstic regression analysis showed that Lp‐PLA2 was one of the risk factors for acute ischemic stroke (OR=4 .213 ,95% CI=2 .345 -9 .865 ,P<0 .05) .Conclusion Levels of Lp‐PLA2 varied in different TOAST sub‐types and the level in AT group was the highest .Lp‐PLA2 was the risk factor in AT subtypes .Therefore ,serum Lp‐PLA2 level can be used to assess the risk of acute ischemic stroke and to help to determine the TOAST subtypes .关键词
急性缺血性脑卒中/脂蛋白相关磷脂酶A2/新TOAST分型Key words
acute ischemic stroke/Lp-PLA2/new-TOAST引用本文复制引用
赵培,李永辉,高伟,霍丽静,于悦卿,帖彦清..急性缺血性脑卒中 Lp-PLA2水平与新 TOAST 分型关系的探究[J].检验医学与临床,2016,13(9):1177-1178,1183,3.基金项目
河北省医学科学研究重点课题项目（20150130）。 （）
