摘要
Abstract
Objective To explore the diagnostic value in children with acute upper respiratory tract infection by using bedside diagnosis(POCT) method to detect whole blood level of serum amyloid a protein(SAA) ,hypersensi‐tive C‐reactive protein(hs‐CRP) and C‐reactive protein(CRP) .Methods Analyzed whole blood SAA ,hs‐CRP ,CRP and white blood cell(WBC) in 71 cases of children with acute upper respiratory tract infection and normal control group by using the POCT method ,and compared the cutoff value and sensitivity and specific degrees of each index with ROC curve .Results The level of SAA ,hs‐CRP and CRP in children with acute upper respiratory tract infection were higher than normal control group and their difference all had statistically significance(tSAA =6 .395 ,P<0 .05 ;ths‐CRP =8 .516 ,P<0 .05 ;tCRP =3 .419 ,P<0 .05) .The area under the curve ,sensitivity and specificity of SAA and hs‐CRP were 0 .830 ,0 .823;69 .0% ,81 .7% and 96 .0% ,74 .7% ,respectively .Conclusion Detecting whole blood SAA , hs‐CRP and CRP by POCT method can help the early diagnosis and prognosis of pediatric acute upper respiratory tract infection disease .Among those detection index ,SAA and hs‐CRP is more sensitive .关键词
急性上呼吸道感染/血清淀粉样蛋白/超敏C反应蛋白Key words
acute upper respiratory tract infection/serum amyloid protein/hypersensitive C-reactive pro-tein
