临床神经病学杂志2016,Vol.29Issue(2):117-119,3.
大动脉粥样硬化性脑梗死患者伴发低三碘甲状腺原氨酸综合征的危险因素及预后分析
Analysis of risk factors and prognosis in patients with cerebral infarction due to large artery atherosclerosis combined with low triiodothyronine syndrome
吴德峰 1吴冠会 2董晓峰 2孔凡贞 3程庆璋 2罗蔚锋1
作者信息
- 1. 215002苏州大学附属第二医院神经内科
- 2. 南京医科大学附属苏州医院 苏州市立医院 本部神经内科
- 3. 苏州大学附属广济医院临床心理科
- 折叠
摘要
Abstract
Objective To explore the risk factors and the prognosis in cerebral infarction due to large artery atherosclerosis ( LAA-CI ) patients combined with low triiodothyronine ( T3 ) syndrome ( LTS ) .Methods Two hundred and eight patients with acute LAA-CI were divided into two groups based on examined thyroid hormone levels.Clinical data on admission and mRS at one year after the event were collected and analyzed.Results There were 151 cases of patients with normal T3 levels (control group) and 57 cases of patients with LTS (LTS group). Compared with patients in control group, the T3 level of LTS group was significantly decreased, while the thyroid stimulating hormone level was significantly increased (all P<0.01).Age, systolic blood pressure, NIHSS score on admission and proportion of patients with diabetes mellitus in LTS group were significantly higher than those in control group (all P<0.05).Logistic regression analysis showed that age and NIHSS on admission were closely related with incidence of LTS (all P<0.01).The proportion of patients with mRS 3-6 or 6 at one year after the event in LTS group was significantly higher than that in control group ( all P<0.01 ) .Conclusions The prognosis of LAA-CI patients combined with LTS is poor.Aged and severe neurological deficits may be the independent risk factors of which.关键词
大动脉粥样硬化型脑梗死/低三碘甲状腺原氨酸综合征/危险因素/预后Key words
cerebral infarction due to large artery atherosclerosis/low triiodothyronine syndrome/risk fac-tors/prognosis分类
医药卫生引用本文复制引用
吴德峰,吴冠会,董晓峰,孔凡贞,程庆璋,罗蔚锋..大动脉粥样硬化性脑梗死患者伴发低三碘甲状腺原氨酸综合征的危险因素及预后分析[J].临床神经病学杂志,2016,29(2):117-119,3.