临床神经病学杂志2016,Vol.29Issue(2):120-123,4.
病毒性脑炎后癫痫的预后及其影响因素
Prognosis and its influencing factors of post-encephalitic epilepsy
马海燕 1张燕芳 1狄晴1
作者信息
- 1. 210029南京医科大学附属脑科医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the prognosis and its influencing factors of post-encephalitic epilepsy ( PEE) .Methods Fifty viral encephalitis patients with PEE were followed up, which prognosis was observed by whether their no seizures for at least 1 year or not.The clinical data of patients was collected, and the relate risk factors on the poor prognosis of PEE were analyzed.Results The disturbance of consciousness and the seizure presence during acute encephalitis, more than ten seizures in poor prognosis group were much higner than the good one (all P<0.01).The age, sex, seizure type, dysphrenia and neurological defect in acute encephalitis, status epileptisus in acute encephalitis, abnormal EEG and abnormal head CT/MRI had no correlation with poor prognosis ( all P>0.05 ) .Multiple logistic regression analysis demonstrated that disturbance of consciousness during acute encephalitis、seizures presence in acute encephalitis were independent risk factors of poor outcome in PEE ( OR=7.269,95%CI:1.22 -43.35,P=0.029;OR =22.893,95%CI:4.02 -130.43,P=0.000).Conclusion Disturbance of consciousness during acute encephalitis, seizure presence in acute encephalitis both are the single risk factors of poor prognosis in PEE.关键词
病毒性脑炎/脑炎后癫痫/危险因素/预后Key words
viral encephalitis/post-encephalitic epilepsy/risk factors/prognosis分类
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马海燕,张燕芳,狄晴..病毒性脑炎后癫痫的预后及其影响因素[J].临床神经病学杂志,2016,29(2):120-123,4.