国际眼科杂志2016，Vol.16Issue(5)：852-855,4.DOI:10.3980/j.issn.1672-5123.2016.5.15
免疫球蛋白G4相关性眼眶病的临床研究进展
Current clinical research of immunoglobulin G4-related orbital disease
摘要
Abstract
lmmunoglobulin G4 - related disease ( lgG4 - related disease ) has received lots of attention in medical community as a recently recognized fibro-inflammatory condition. lt is characterized by infiltration of lgG4 -immunopositive plasmacytes and concentration of elevated serum lgG4. lgG4-related disease shows organ enlargement or nodular/hyperplastic lesions in various organs including the pancreas, hepatobiliary tract and orbit, which is called lgG4-related orbital disease. The diagnostic criteria for lgG4-related disease and lgG4-related orbital disease has recently been established, which is based on clinical, imaging and histopathologic features of the orbital lesions. Besides, attention should be drawn to the differentiation from other diseases. The treatment is empirical including corticosteroids, immunosuppressive drugs, radiotherapy, and rituximab. This article reviews clinical progression of lgG4-related orbital disease.关键词
免疫球蛋白G4相关性眼眶病/眼眶病/免疫球蛋白G4相关性疾病/自身免疫性疾病Key words
immunoglobulin G4 - related orbital disease/orbital disease/immunoglobulin G4 - related disease/autoimmune disease引用本文复制引用
王洋,周慧芳,范先群..免疫球蛋白G4相关性眼眶病的临床研究进展[J].国际眼科杂志,2016,16(5):852-855,4.基金项目
国家高技术研究发展计划(863计划)( No.2015AA020311)@@@@National High Technology Research and Developlent Progral(863 Progral)(No.2015AA020311) （863计划）
