中南医学科学杂志2016，Vol.44Issue(2)：147-149,3.DOI:10.15972/j.cnki.43-1509/r.2016.02.007
胶质瘤中P ar6蛋白的表达及其临床病理学意义
The Expression and Clinical Pathological Significance of Par6 in Glioma
徐刚 1洪丽 1蒋穗斌1
作者信息
- 1. 南华大学医学院临床技能中心，湖南 衡阳421001
- 折叠
摘要
Abstract
Objective To explore the role of Par6 in the development of glioma by analysis of the expression of Par6 in glioma tissue. Methods 70 cases of human glioma tissue with different clinical period and differentiation histological type and 20 cases of normal brain tissue were selected.The protein of Par6 was detected by immunohistochemistry. Results Compared with normal brain tissue,the expression of Par6 protein in glioma tissue decreased significantly (P<0. 05).The expression level of Par6 was lower at stageⅢ~Ⅳthan that atⅠ~Ⅱ(Ⅰ~ⅡvsⅢ~Ⅳ;P=0.008) . Conclusion The expression of Par6 in glioma tissue decreased,and Par6 was involved in the development and progression of glioma,which was markedly correlated with clinical stage.关键词
胶质瘤/Par6/侵袭/临床分期Key words
Par6/Glioma/invasion/clinical stage分类
医药卫生引用本文复制引用
徐刚,洪丽,蒋穗斌..胶质瘤中P ar6蛋白的表达及其临床病理学意义[J].中南医学科学杂志,2016,44(2):147-149,3.
