四川医学2016,Vol.37Issue(4):430-432,3.DOI:10.16252/j.cnki.issn1004-0501-2016.04.020
非血液标本的1,3-β-D-葡聚糖检测对放疗后侵袭性真菌感染的诊断价值
Diagnosis Value of Non-blood Samples of 1,3-β-D-Dextran Testing in Invasive Fungal Infection after Radiotherapy
姚力偀 1唐友东2
作者信息
- 1. 绵阳市中心医院检验科,四川 绵阳621000
- 2. 峨眉山市中医院检验科,四川 峨眉山614200
- 折叠
摘要
Abstract
Objective To evaluate the diagnostic value of 1,3-β-D-dextran in non-blood samples for radioactive pulmo-nary fungal infection. Methods The differences of the expression of 1,3-β-D- dextran(1,3-beta-D-glucan,BG) in blood,airway secretions and pleural effusion of lung cancer patients after radiotherapy were analyzed. Results G test results of different speci-mens were different in the diagnostic efficacy of the patients with radioactive pulmonary fungal infection. Sensitivity,accuracy and specificity of blood samples were the highest. And the positive predictive value and negative predictive value were optimal for the pleural effusion. Conclusion In the positive judgement threshold of G test is ≥10pg/mL,G test results of pleural effusion and airway secretions could detect lung fungal infection in patients with lung cancer after radiotherapy.关键词
肺癌/放疗/侵袭性真菌感染/1 ,3-β-D-葡聚糖/非血液标本Key words
lung cancer/radiotherapy/invasive fungal infection/1,3-β-D-dextran/non-blood samples分类
医药卫生引用本文复制引用
姚力偀,唐友东..非血液标本的1,3-β-D-葡聚糖检测对放疗后侵袭性真菌感染的诊断价值[J].四川医学,2016,37(4):430-432,3.