药学研究2016，Vol.35Issue(4)：222-225,4.DOI:10.13506/j.cnki.jpr.2016.04.010
白藜芦醇纳米混悬液的制备及固化
The preparation of resveratrol nano - suspensions and its solidification
刘凯 1童达君 1何媛1
作者信息
- 1. 江苏恒瑞医药股份有限公司，国家靶向药物工程技术研究中心，江苏 连云港 222047
- 折叠
摘要
Abstract
Objective To prepare resveratrol nano - suspensions and solidify the suspensions. Methods Resveratrol nano - suspensions were obtained by anti - solvent precipitation and high pressure homogenization,and the suspensions were solidified by freezing - drying process. Results Anti - solvent precipitation was chosen to prepared resveratrol nano - sus-pensions with mean particle size of prepared nanoparticle was 120. 3 nm. After solidification,the dissolution rate of resvera-trol was significantly improved using in vitro experiment assay. Conclusion The method used to prepare resveratrol nano -suspension was simple. It was suitable for preparing capsules or tablets after solidification.关键词
白藜芦醇/纳米混悬液/固化/高压均质Key words
Resveratrol/Nanosuspension/Solidification/High pressure homogenization分类
医药卫生引用本文复制引用
刘凯,童达君,何媛..白藜芦醇纳米混悬液的制备及固化[J].药学研究,2016,35(4):222-225,4.
