现代医药卫生2016，Vol.32Issue(9)：1287-1289,3.DOI:10.3969/j.issn.1009-5519.2016.09.003
代谢综合征与无症状性颅内动脉狭窄的相关性研究
Correlation between metabolic syndrome and asymptomatic intracranial arterial stenosis
摘要
Abstract
Objective To investigate the correlation between metabolic syndrome and asymptomatic intracranial arterial stenosis. Methods Metabolic syndrome was diagnosed according to the criteria recommended by the Chinese Diabetes Society of the Chinese Medical Association. Totally 526 patients with middle cerebral artery stenosis diagnosed by transcranial Doppler in our hospital from January to June 2015 were taken as the case group and other 526 subjects without intracranial arterial stenosis as the control group. The differences of anthropometric indices ,biochemical indices and prevalence rate were compared between the two groups. All the research subjects were divided into the group M1,2,3,4,5 for analyzing the relationship between the abnormal in dexes number with the prevalence rate of intracranial arterial stenosis and calculating the odds ratio (OR). Results The body mass index,waist circumstance,systolic blood pressure,diastolic blood pressure,levels of total cholesterol,triglyceride,low density lipoprotein cholesterol and fasting blood glucose,and prevalence rate of diabetes,hypertension and metabolic syndrome in the case group were significantly higher than those in the control group,and the differences were statistically significant(P<0.01),while the high density lipoprotein cholesterol level in the case group was significantly lower than that in the control group ,and the difference was statistically significant(P<0.01). With the number of abnormal indices in the group M2,3,4,5 increasing from 1 to 4,the detection rate of intracranial arterial stenosis was gradually increased ,and the difference was statistically significant compared with the group M1(P<0.01). In calculating the OR value in each group with the M1 group as the baseline,the OR value in the group M2,3,4,5 was gradually increased compared with that in the group M1. Conclusion Metabolic syndrome is an important risk factor of asymp-tomatic intracranial arterial stenosis. Each abnormal index of metabolic syndrome should be better controlled in order to reduce the risk of intracranial arterial stenosis.关键词
代谢综合征X/颈动脉疾病/颅骨/脑动脉/缩窄,病理性Key words
Metabolic syndrome X/Carotid artery diseases/Skull/Cerebral arteries/Constriction,pathologic引用本文复制引用
李永强,王永红,王小林,高杨毅..代谢综合征与无症状性颅内动脉狭窄的相关性研究[J].现代医药卫生,2016,32(9):1287-1289,3.基金项目
重庆市科技惠民计划资助项目（CSTC2015JCSF10012）。 （）
