现代医药卫生2016，Vol.32Issue(10)：1465-1467,3.DOI:10.3969/j.issn.1009-5519.2016.10.010
溪黄草抗乙型肝炎病毒体外抑制作用研究
Study on in vitro inhibiting effect of Rabdosia Serra in anti-HBV
庞琼 1胡志立2
作者信息
- 1. 郴州市疾病预防控制中心体检科，湖南423000
- 2. 湘南学院胃肠外科，湖南郴州423000
- 折叠
摘要
Abstract
Objective To provide an important scientific basis for verifying the in vitro anti-HBV activity of single herb Rabdosia Serra. Methods 50%ethanol extract of Rabdosia Serra was dispensed as certain concentrations. The HepG2.2.15 cel-lular model was adopted to conduct the cellular toxicity test and HBsAg and HBeAg enzyme-linked immunosorbent ssay(ELISA). Results IC50 was 4.275 mg/mL,IC50 of crude extract of Rabdosia Serra on HBsAg was 2.250 mg/mL,which on HBeAg was 2.150 mg/mL,the therapeutic index(TI)<2. Conclusion The crude extract of Rabdosia Serra has the effect for in vitro inhibiting HBV.关键词
溪黄草/肝炎病毒,乙型/细胞培养技术/植物,药用/细胞毒性试验,免疫Key words
Isodon striatus/Hepatitis B virus/Cell culture techniques/Plants,medicinal/Cytotoxicity tests, immunologic引用本文复制引用
庞琼,胡志立..溪黄草抗乙型肝炎病毒体外抑制作用研究[J].现代医药卫生,2016,32(10):1465-1467,3.
