中国医疗设备2016,Vol.31Issue(4):6-13,29,9.DOI:10.3969/j.issn.1674-1633.2016.04.002
电磁医疗设备的生物物理基础与应用
Biological and Physical Principles and Applications of Electromagnetic Medical Devices
摘要
Abstract
Electromagnetic medical devices refer to a category of equipment used for medical diagnosis and treatment by utilizing electric field, magnetic field, or electromagnetic field. Electromagnetic biological effects including the thermal effects and non-thermal effectsare the main principle and the bases of assessment for innovative electromagnetic medical devices. Physical factors influencing the biological effects include electromagnetic energy as well as permittivity and permeability of organisms. Thermal effects are evidenced by temperature rise. The cells do not suffer from obvious injury, such as the reversible and/or irreversible damage injury caused by the process of coagulation, drying, carbonization or vaporization, which make it able to be applied in high-frequency therapy, microwave tumor therapy, radiofrequency ablation, electric surgery,etc. Non-thermal effects is evidenced bybiochemical and physiological response in the molecules, cells, tissues, organs and body with no temperature rise in the organism when exposed to the electromagnetic field, which can be applied to pacemakers, heart defibrillation, extracorporeal shock wave lithotripsy, and so on. In recent years, research has carried out in both the basic principles and equipment of electromagnetic medical devices. Some electromagnetic medical devices were developed, such as electromagnetic-phoresis apparatuses, transdermal drug delivery, and irreversible electroporation tumor therapy. Effective means of safety control of electromagnetic medical device is to establish the electromagnetic limit standard and to implement according to the standard based on human physiological integrity.关键词
电磁医疗设备/生物效应/经皮给药/电磁导入/驻极体/不可逆电穿孔/电磁限值标准Key words
electromagnetics medical device/biological effects/transdermal drug delivery/electromagnetic-phoresis/electret/irreversible electroporation/electromagnetic limits tandard分类
医药卫生引用本文复制引用
包家立..电磁医疗设备的生物物理基础与应用[J].中国医疗设备,2016,31(4):6-13,29,9.基金项目
国家自然科学基金(61071060)。 ()