医学信息2016，Vol.29Issue(12)：68-69,2.
恶性肿瘤并发蛋白尿患者治疗后尿的变化及临床意义探讨
Changes of Urine and Its Clinical Significance in Patients with Malignant Tumor Complicated with Proteinuria
摘要
Abstract
Objective To observe urine changes after treatment of patients with malignant tumor complicated with proteinuria,and explore the clinical significance.And to provide basis for clinical prevention and treatment.Methods Adopting the method of retrospective study,367 malignant treated in hospital were selected from January in 2010 to September in 2014, including 170 patients with proteinuria who were as the observation group,197 patients without concurrent proteinuria,as the control group.Observed the main clinical stage, metastasis, clinical symptoms change,survival time of the two groups and clinical symptoms result of varying different degrees proteinuria.Results stage and tumor metastasis of the observation group were 80.59%(137/170) and 75.88%(129/170) , higher than the control group 54.82%(108/197) and 42.64%(84/197),the differences was statistically significant ( <0.05).No change or increase of the clinical symptoms of the observation group was 55.29% (94/170),higher than the control group 36.55% (72/197),the differences was statistically significant( <0.05).The disappeared or clinical remission of the clinical symptoms of the observation group were 10.59%(18/170)and 10.59%(58/170),lower than the control group 16.75%(33/197) and 46.70% (92/197),the differences were statistically significant ( <0.05). The survival time<6 month of the observation group was 81.18% (138/170),higher than the control group 38.58% (76/197),the differences were statistically significant( <0.05),The average survival time of the observation group was (5.481.25) month,lower than the control group (14.29±1.56)months,the differences were statistically significant ( <0.05).No change or worsening of clinical symptoms of proteinuria degree +++was 68.93% (71/103),higher than proteinuria~++34.33% (23/67),symptoms disappeared of proteinuria degree+++was 4.85% (103/103),lower than proteinuria++19.40%(13/67),the differences was statistically significant( <0.05).Conclusion Patients with cancer complicated by proteinuria mostly advanced lesions appear and metastasis in patients with clinical symptoms worsened after more,and with the degree of proteinuria aggravation aggravated significantly reduced survival time of patients.关键词
恶性肿瘤/蛋白尿/尿液检测/临床意义Key words
Malignant tumor/Proteinuria/Urine test/Clinical significance引用本文复制引用
韩鹦赢..恶性肿瘤并发蛋白尿患者治疗后尿的变化及临床意义探讨[J].医学信息,2016,29(12):68-69,2.基金项目
天津市卫生局科技基金蛋白尿发生、预后多因素相关分析及对妊娠结局影响2013KZ024。 （）
