中国全科医学2016，Vol.19Issue(14)：1659-1662,4.DOI:10.3969/j.issn.1007-9572.2016.14.011
瞬时弹性测定仪测定受控衰减参数在脂肪性肝病中的应用价值
Value of FibroScan in the Detection of Controlled Attenuation Parameters for Fatty Liver Disease
摘要
Abstract
Objective To investigate the value of FibroScan in the detection of controlled attenuation parameters (CAP)for distinguishing fatty liver disease(FLD)patients with different etiological factors. Methods From October 2013 to December 2014,we enrolled 524 patients who received ultrasonic examination of liver stiffness and fatty change and were definitely diagnosed as FLD in Beijing Shijitan Hospital,Capital Medical University. According to etiological factors,the patients were divided into three groups:NAFLD group(n = 406),CHB + NAFLD group(n = 69)and ALD group(n = 49). We also enrolled 48 patients with AMA-M2 positive as AMA-M2 group. All the patients were diagnosed as FLD by abdominal ultrasound. The general data of the patients were recorded,and the detection of liver function and blood lipid were also conducted. Doctors who had received special training measured CAP value. They captured echos for 10 times between the 7th and 8th rib of the right axillary front and the right midaxillary line,and took the median as CAP. Results Different groups were not significantly different in the levels of ALT,ALP,TG,LDL-C and HDL-C( P > 0. 05). Different groups were significantly different in gender,age,BMI,AST,GGT and TC(P < 0. 05). Different groups were significantly different in CAP( P <0. 05);CHB + NAFLD group,ALD group and AMA-M2 group were lower than NAFLD group in CAP,and CHB + NAFLD group was lower than ALD group in CAP(P < 0. 05). Conclusion The application of FibroScan in the determination of CAP could help distinguish FLD patients with different etiological factors.关键词
脂肪肝/受控衰减参数/脂肪肝,酒精性/乙型肝炎,慢性/自身免疫性肝病Key words
Fatty liver/Controlled attenuation parameter/Fatty liver, alcoholic/Hepatitis B, chronic/Autoimmune liver disease分类
医药卫生引用本文复制引用
郭春梅,吴静,王沧海,王亚丹,尹金淑..瞬时弹性测定仪测定受控衰减参数在脂肪性肝病中的应用价值[J].中国全科医学,2016,19(14):1659-1662,4.基金项目
铁道部科技研究开发计划课题 （）
