中国比较医学杂志2016,Vol.26Issue(2):83-86,4.DOI:10.3969/j.issn.1671-7856.2016.02.017
微核试验方法及应用研究进展
Research progress of the methods and applications of micronucleus assay
陈思 1鲁克庆 2马兴铭3
作者信息
- 1. 兰州大学第二医院检验中心
- 2. 兰州大学基础医学院,兰州 730030
- 3. 甘肃省泌尿系疾病临床医学中心
- 折叠
摘要
Abstract
Micronucleus ( MN) assay as a routine examination for genotoxicity has been widely used.The testing specimens were taken from bone marrow and extended from blood and tissues.In addition to testing genotoxicity of drugs, it is also applied in disease diagnosis for genetic mutation, evaluation of curative effectiveness and disease prevention. Moreover, MN assay is also an important safety indicator for drugs and health foods registration.This review will discuss the staining method of MN test and its application in the field of diseases and virology.关键词
微核试验/基因毒/疾病Key words
Micronucleus assay/Genotoxicity/Disease分类
医药卫生引用本文复制引用
陈思,鲁克庆,马兴铭..微核试验方法及应用研究进展[J].中国比较医学杂志,2016,26(2):83-86,4.