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微核试验方法及应用研究进展

陈思 鲁克庆 马兴铭

中国比较医学杂志2016,Vol.26Issue(2):83-86,4.
中国比较医学杂志2016,Vol.26Issue(2):83-86,4.DOI:10.3969/j.issn.1671-7856.2016.02.017

微核试验方法及应用研究进展

Research progress of the methods and applications of micronucleus assay

陈思 1鲁克庆 2马兴铭3

作者信息

  • 1. 兰州大学第二医院检验中心
  • 2. 兰州大学基础医学院,兰州 730030
  • 3. 甘肃省泌尿系疾病临床医学中心
  • 折叠

摘要

Abstract

Micronucleus ( MN) assay as a routine examination for genotoxicity has been widely used.The testing specimens were taken from bone marrow and extended from blood and tissues.In addition to testing genotoxicity of drugs, it is also applied in disease diagnosis for genetic mutation, evaluation of curative effectiveness and disease prevention. Moreover, MN assay is also an important safety indicator for drugs and health foods registration.This review will discuss the staining method of MN test and its application in the field of diseases and virology.

关键词

微核试验/基因毒/疾病

Key words

Micronucleus assay/Genotoxicity/Disease

分类

医药卫生

引用本文复制引用

陈思,鲁克庆,马兴铭..微核试验方法及应用研究进展[J].中国比较医学杂志,2016,26(2):83-86,4.

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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