中国医科大学学报2016，Vol.45Issue(4)：301-304,327,5.DOI:10.12007/j.issn.0258-4646.2016.04.004
经膈脚后间隙穿刺损毁内脏神经治疗胰腺癌疼痛的临床疗效分析
Clinical Efficiency Analysis of Visceral Nerve Plexus Neurolysis through Post-curs of Diaphragm Approach in Pancreatic Cancer Pain Management
摘要
Abstract
Objective To evaluate the clinical effect of computed tomography⁃guided visceral nerve plexus ethanol neurolysis through post⁃curs of diaphragm approach in the treatment of patients with pancreatic cancer pain using,and study the safety and life quality improvement of patients . Methods A total of 58 patients suffered from pancreatic cancer pain,who were treated in the department of pain medicine of the First Hospital of China Medical University from October 2013 to December 2014,were recruited for the study. The patients were divided into two groups according to the willing of the patients and their families,group A(32 cases)was treated with Visceral Nerve Plexus ethanol Neurolysis,while group B(26 cas⁃es)was treated with oral opioid drugs. The analgesic effect,changes in the amount of opioid drugs,changes in the PSQI scores and the improvement of quality of life were evaluated before treatment and 1 day(T1),15 days(T15),30 days(T30),60 days(T60)after treatment. Record the adverse reactions in the course of treatment. Results All the patients of group A successfully received visceral nerve plexus ethanol neurolysis,the VAS scores,Karnofsky scores,and PSQI scores of all the observed time points(after the operation)were statistically different compared to those before treatment and group B. Statistically difference was also observed in quality of life between two groups(P<0.05). The amount of opioid drugs of group B was statistically increased than that of group A(P<0.01).The most common side effects in Group A were postural hypotension(6 cases),diar⁃rhea(2 cases),and intercostal neuralgia,while nausea(20 cases),constipation(11 cases)and dizziness(8 cases)were seen in the Group B. Con⁃clusion Visceral nerve plexus ethanol neurolysis through post⁃curs of diaphragm approach by the guide of CT is effective and safe for the patients with pancreatic cancer pain,and the complications were totally acceptable.关键词
膈脚后间隙/内脏神经/毁损/胰腺癌/疼痛Key words
post-curs of diaphragm/visceral nerve plexus/neurolysis/pancreatic cancer/pain分类
医药卫生引用本文复制引用
于雪,刘妍,奚奇,万成福,董道松,赵林,宋涛..经膈脚后间隙穿刺损毁内脏神经治疗胰腺癌疼痛的临床疗效分析[J].中国医科大学学报,2016,45(4):301-304,327,5.基金项目
国家自然科学基金 （）
