中国医科大学学报2016，Vol.45Issue(4)：305-308,4.DOI:10.12007/j.issn.0258-4646.2016.04.005
双相障碍抑郁相患者静息态脑功能磁共振局部一致性的研究
Altered Regional Homogeneity in Bipolar Depression:A Resting-state Functional Magnetic Resonance Imaging Study
摘要
Abstract
Objective To study the abnormal alteration of regions in bipolar depression patients,so as to investigate its pathophysiologic mecha⁃nism. Methods Regional homogeneity(ReHo)technology of resting⁃state functional magnetic resonance imaging were used to compare 24 bipolar depression patients and 28 healthy controls. Results Compared to the healthy controls,the bipolar depression patients exhibited significantly higher ReHo value in the bilateral superior frontal gyrus,the bilateral middle frontal gyrus,the bilateral medial frontal cortex,the bilateral supplementary motor area,the left paracentral lobule and the left precentral gyrus(all P<0.001). Conclusion The abnormal function in the bilateral superior frontal gyrus,the bilateral middle frontal gyrus,the bilateral medial frontal cortex,the bilateral supplementary motor area,the left paracentral lobule and the left precentral gyrus may associate with the mechanism of pathophysiology in bipolar depression.关键词
双相障碍/抑郁相/静息状态/功能磁共振/局部一致性Key words
bipolar depression/resting-state/functional magnetic resonance imaging/regional homogeneity分类
医药卫生引用本文复制引用
姜晓薇,周千,汤艳清,王菲..双相障碍抑郁相患者静息态脑功能磁共振局部一致性的研究[J].中国医科大学学报,2016,45(4):305-308,4.基金项目
国家自然科学基金 （）
