中国医科大学学报2016，Vol.45Issue(4)：318-323,6.DOI:10.12007/j.issn.0258-4646.2016.04.008
阿片类药物预处理对依托咪酯注射所致肌阵挛影响的meta分析
Effect of Opiod Pretreatments on Etomidate Induced Myoclonus:A Meta-analysis
摘要
Abstract
Objective To assess the effect of opiod pretreatment on etomidate induced myoclonus. Methods The pertinent literatures were searched by two independent investigators from the following electronic databases:PubMed,Cochrane Library,EMbase,VIP,WanFang Data,and CHKD. Then the meta⁃analysis was performed by using RevMan 5.2 and STATA 12.0 software. Results A total of 24 RCTs involving 2 396 pa⁃tients were included for the study. Pretreatment ofμorκ⁃receptor agonists reduced myoclonus with RR=0.19(95%CI 0.14 to 0.27)and RR=0.22 (95%CI 0.12 to 0.40),respectively. Conclusion Pretreatment of opiods can reduce the incidence of etomidate induced myoclonus.关键词
依托咪酯/肌阵挛/阿片/meta分析Key words
etomidate/myoclonus/opiod/meta-analysis分类
医药卫生引用本文复制引用
邱鹏,邱爽,董有静..阿片类药物预处理对依托咪酯注射所致肌阵挛影响的meta分析[J].中国医科大学学报,2016,45(4):318-323,6.基金项目
辽宁省自然科学基金 （）
