中国医科大学学报2016，Vol.45Issue(5)：422-425,4.DOI:10.12007/j.issn.0258-4646.2016.05.010
18F-FDG PET/CT显像对胃肠肿瘤术后肠梗阻病因学的诊断价值
Clinical Significance of 18F-FDG PET/CT in the Etiological Diagnosis of Postoperative Intestinal Obstruction in Patients with Gastrointestinal Cancer
摘要
Abstract
Objective To explore the significance of 18fluorodeoxyglucose positron emission tomography(18F⁃FDG PET/CT)in the etiological diag⁃nosis of postoperative intestinal obstruction in patients with gastrointestinal cancer. Methods A total of 51 patients with postoperative intestinal ob⁃struction undergone 18F⁃FDG PET/CT were enrolled for the study. The images were interpreted by visual and semi⁃quantitative analysis(maximum standard uptake value,SUVmax). All the cases were confirmed by pathology and clinical follow⁃up for more than half a year. The sensitivity,specifici⁃ty and accuracy of 18F⁃FDG PET/CT for detecting malignant intestinal obstruction were calculated. Results Of the 51 patients,35 cases were con⁃firmed for malignant intestinal obstruction,and 16 cases were caused by other benign diseases. 18F⁃FDG PET/CT imaging was positive in 36 cases, and 33 cases were diagnosed as malignant and recurrent intestinal obstruction. Three cases of PET false⁃positive were peritonitis adhesion and anasto⁃motic inflammation. Two cases of PET false negative were peritoneal micrometastasis. The SUVmax of malignant lesions was 8.86±4.82,and the SUVmax of benign lesions was 2.05±1.95. The uptake of FDG was significantly higher in malignant intestinal obstruction than in benign intestinal obstruction (t=7.15,P<0.01). The sensitivity,specificity,and accuracy of 18F⁃FDG PET/CT diagnosis of malignant lesion were 94.3%,81.3%,and 90.2%, respectively. Conclusion The uptake of 18F⁃FDG in malignant intestinal obstruction was higher than that in benign intestinal obstruction. 18F⁃FDG PET/CT have a good diagnostic value for the intestinal obstruction of postoperative gastrointestinal cancer.关键词
肠梗阻/正电子发射断层显像术/X线计算机体层摄影术Key words
intestinal obstruction/positron emission-tomography/X-ray computed tomography分类
医药卫生引用本文复制引用
李雪娜,李娜,杜补林,李亚明..18F-FDG PET/CT显像对胃肠肿瘤术后肠梗阻病因学的诊断价值[J].中国医科大学学报,2016,45(5):422-425,4.基金项目
国家自然科学基金（81301249）；辽宁省科学技术计划 （）
