中国医科大学学报2016，Vol.45Issue(5)：434-437,4.DOI:10.12007/j.issn.0258-4646.2016.05.013
吉兰-巴雷综合征患者神经电生理特点及其与机械通气、远期预后的相关性分析
Correlation Analysis between Electrophysiological Features and Mechanical Ventilation and Long-term Outcome in Patients with Guillain-Barré Syndrome
摘要
Abstract
Objective To study the correlation between the electrophysiological features and mechanical ventilation and long⁃term outcome in Guil⁃lain⁃Barré syndrome(GBS)patients. Methods Electrophysiological and clinical data were retrospectively collected,and compared between venti⁃lated and not ventilated patients,as well as among each subtype of GBS. Results Totally 38 GBS patients were included in the study,among which 12(32%)were ventilated. The p/d CMAP ratio of the common peroneal nerve was significantly lower in ventilated group compared to not ventilated group(48.7±15.3 vs 80.8±24.0,P=0.005). AIDP was the most common subtype in ventilated patients compared with AMAN and undetermined (46%vs 0%and 9%,P=0.027). The long⁃term outcome score of AMAN was significantly lower than AIDP(4.3±1.3 vs 2.5±0.9,P=0.028). Conclusion Electrophysiological testing was predictive for mechanical ventilation and long⁃term outcome:low p/d CMAP ratio of the common pero⁃neal nerve was helpful for predicting mechanical ventilation,AIDP was prone to develop respiratory failure and had a worse outcome compared to AMAN.关键词
吉兰-巴雷综合征/神经电生理/机械通气/远期预后Key words
Guillain-Barré syndrome/electrophysiology/mechanical ventilation/long-term outcome分类
医药卫生引用本文复制引用
朱皓月,李妍,金娟,赵珊珊,曲慧玲,赵传胜..吉兰-巴雷综合征患者神经电生理特点及其与机械通气、远期预后的相关性分析[J].中国医科大学学报,2016,45(5):434-437,4.基金项目
辽宁省自然科学基金 （）
