中华耳科学杂志2016，Vol.14Issue(1)：21-26,6.DOI:10.3969/j.issn.1672-2922.2016.01.005
小型猪肌源性诱发前庭电位的检测
Vestibular-evoked myogenic potentials in miniature pigs
摘要
Abstract
Objective To report detection of vestibular-evoked myogenic potentials (VEMP) in the miniature pig. Methods Potentials evoked by 1000 Hz tone bursts were recorded from neck extensor muscles and the masseter muscles in normal adult Bama miniature pigs anesthetized with 3%pentobarbital sodium and Sumianxin II. Results The latency of the first positive wave P from neck extensor muscles was 7.65 ± 0.64 ms, with an amplitude of 1.66 ± 0.34 uv and a rate of suc-cessful induction of 75%at 80 dB SPL. The latency of potentials evoked from the masseter muscles was 7.60±0.78 ms, with an amplitude of 1.31 ± 0.28 uv and a rate successful induction of 66%at 80 dB SPL. Conclusion The latencies and thresh-olds of VEMPs recorded from neck extensor muscles and the masseter muscles appear to be comparable in normal adult Bama miniature pigs, although the amplitude recorded from neck extensor muscles seems to be higher than that from the masseter muscles. However, because of their usually relatively superficial and easily accessible location, as well as their large volume and strong contractions, masseter muscles may be better target muscles for recording myogenic potentials.关键词
肌源性诱发前庭电位/小型猪/咬肌肌源性诱发前庭电位Key words
vestibular evoked myogenic potentials/miniature pig/masseter myogenic potential分类
医药卫生引用本文复制引用
李亚,杨仕明,乔月华,张悦,赵立东,郭维维,潘红梅,张亮,袁硕龙,任丽丽,时晰..小型猪肌源性诱发前庭电位的检测[J].中华耳科学杂志,2016,14(1):21-26,6.基金项目
国家973计划重大科学研究计划干细胞项目（2012CB967900）；国家973计划重大科学问题导向项目（2011CBA01000)；国家自然科学基金（面上项目81271082，81470684，青年项目81400472）；江苏省临床医学科技专项b12014032，江苏省六大人才高峰2014-WSN-043,中国博士后基金2015M571818，江苏省高等学校大学生创新创业训练计划201510313003Z；重庆市基本科研业务费项目（11611，14440）。 （）
