中华耳科学杂志2016，Vol.14Issue(1)：27-31,5.DOI:10.3969/j.issn.1672-2922.2016.01.006
小型猪与大鼠不同记录部位诱发VEMP的比较
Vestibular-evoked myogenic potentials recorded from miniature pigs and rats
摘要
Abstract
Objective To report vestibular evoked myogenic potentials from different recording sites (neck extensor muscle and masseter muscle) in mini pigs and rats. Methods Potentials were recorded from neck extensor muscles or masse-ter muscles in normal adult Bama mini pigs and rats anesthetized with 3% pentobarbital sodium and Sumianxin II using 1000 Hz tone bursts. Results At 80 dB SPL, the latency, amplitude and response rate of the first positive wave P was 6.45± 0.23 ms, 1.45 ± 0.49 uv and 58%, respectively, from rat neck extensor muscles;6.38 ± 0.34 ms, 1.57 ± 0.35 uv and 50%from rat masseter muscles;7.65 ± 0.64 ms, 1.66 ± 0.34 uv and 58%from mini pig neck extensor muscles;and 7.65 ± 0.64 ms,.31 ± 0.28 uv and 50% from mini pig masseter muscles. Conclusion VEMP can be recorded from neck extensor and masseter muscles in mini pigs and rats. Within a given species, VEMP amplitude and response rate are dependent on the site of record-ing, while latency is not. Analysis of the responses suggests that the optimal VEMP recording site is the masseter muscle in mini pigs but cervical extensor muscles in rats. At the same recording site, the latency and amplitude of VEMP are slightly greater in mini pigs than in rats.关键词
前庭诱发肌源性电位/小型猪/大鼠/颈部伸肌肌源性电位/咬肌肌源性电位Key words
vestibular evoked myogenic potentials/mini pig/rat/masseter muscle myogenic potential分类
医药卫生引用本文复制引用
李亚,袁硕龙,张悦,潘红梅,任丽丽,张亮,时晰,乔月华..小型猪与大鼠不同记录部位诱发VEMP的比较[J].中华耳科学杂志,2016,14(1):27-31,5.基金项目
国家973计划重大科学研究计划干细胞项目（2012CB967900）；国家973计划重大科学问题导向项目（2011CBA01000) （）
国家自然科学基金青年项目 （）
重庆市基本科研业务费项目 （）
江苏省六大人才高峰2014-WSN-043 （）
中国博士后基金2015M571818 （）
江苏省高等学校大生创新创业训练计划201510313003Z （）
