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相关视觉刺激抑制听觉相关电位研究

刘佳浩 李小兰 黄茵莉 梁茂金 张雪媛 蔡跃新 陈玲 郑亿庆 杨海弟 陈穗俊 张志钢

中华耳科学杂志2016,Vol.14Issue(1):53-56,4.
中华耳科学杂志2016,Vol.14Issue(1):53-56,4.DOI:10.3969/j.issn.1672-2922.2016.01.011

相关视觉刺激抑制听觉相关电位研究

Related visual stimuli inhibit auditory processing:evidence from event-related potentials

刘佳浩 1李小兰 1黄茵莉 1梁茂金 1张雪媛 1蔡跃新 1陈玲 1郑亿庆 1杨海弟 1陈穗俊 1张志钢1

作者信息

  • 1. 中山大学孙逸仙纪念医院耳鼻喉科中山大学听力与言语疾病研究所
  • 折叠

摘要

Abstract

Objective This study is to investigate the interaction in visual and auditory cortical process-ing, through audiovisual stimulus ERP combined with topomapping and source analysis. Methods Nineteen normal young volunteers were recruited, aged from 22-30 years. All the subjects undertook audiovisual (vow-el [a] vs. vowel [i]), as well as visual and auditory ERP tests. ERP waves under different stimuli were com-pared. Results Audiovisual stimuli evoked visual N1 and N2, and also a positive wave at about 600 ms. Visu-al stimulus evoked ERPs were consistent with the visual part of responses to auditory visual stimuli. Howev-er, P1 amplitude evoked by audiovisual stimuli was lower than that evoked by auditory stimuli alone (p=0.04), and topomapping showed that its distribution was close to the visual cortex. Conclusions Related visu-al stimuli appear to inhibit auditory responses, and cause the auditory response active areas to shift toward the visual response area. The results suggest that in the process of hearing rehabilitation training, avoiding visual stimuli (lip reading) may improve outcomes, although further research is very much needed.

关键词

视听联合刺激/事件相关电位/皮层可塑性

Key words

audiovisual combined stimulus/event related potential/cortical plasticity

分类

医药卫生

引用本文复制引用

刘佳浩,李小兰,黄茵莉,梁茂金,张雪媛,蔡跃新,陈玲,郑亿庆,杨海弟,陈穗俊,张志钢..相关视觉刺激抑制听觉相关电位研究[J].中华耳科学杂志,2016,14(1):53-56,4.

基金项目

国家自然科学基金资助项目 ()

中华耳科学杂志

OA北大核心CSCDCSTPCD

1672-2922

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