中华临床免疫和变态反应杂志2016,Vol.10Issue(1):52-56,5.DOI:10.3969/j.issn.1673-8705.2016.01.010
系统性红斑狼疮并发银屑病15例临床特点
Clinical Characteristics of Coexistence of Systemic Lupus Erythematosus and Psoriasis:A Report of 15 Cases
陈蚞 1刘淑毓 2吴秀华 1郑文洁3
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院风湿免疫科,风湿免疫病学教育部重点实验室,北京 100730
- 2. 福建医科大学附属闽东医院风湿免疫科,福建宁德 355000
- 3. 赤峰学院附属医院风湿免疫科,内蒙古自治区赤峰 024000
- 折叠
摘要
Abstract
Objective The coexistence of systemic lupus erythematosus(SLE)and psoriasis(Ps)is rare.We aimed to investigate the clinical characteristics of coexistence of SLE and Ps and explore the potential coexistence mechanisms.Methods Medical data of patients with coexistent SLE and Ps admitted to Peking Union Medical College Hospital from 1990 to 2015 were reviewed retrospectively.Results A total of 15 patients (13 female and 2 male)with a mean age of(36.7 ±12.97)years developed coexistent SLE and Ps.Among them,12 cases (12/15,80%)developed Ps prior to the diagnosis of SLE,and 3 cases after the diagnosis of SLE.The median interval between the diagnosis of Ps and SLE was 8 years.The most common symptoms of SLE were cutaneous and mucosal manifestations (13/15,86.67%)and muscle and joint involvement (12/15,80.00%).Psoriasis vulgaris (10/15,66.67%)is the most common type of psoriasis.Conclusions Ps can coexistent with SLE.Ps usually presents prior to SLE, and psoriasis vulgaris is the most common type.The association between SLE and Ps is still not clear,which need further studies.关键词
系统性红斑狼疮/银屑病/共存Key words
systemic lupus erythematosus/psoriasis/coexistence分类
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陈蚞,刘淑毓,吴秀华,郑文洁..系统性红斑狼疮并发银屑病15例临床特点[J].中华临床免疫和变态反应杂志,2016,10(1):52-56,5.