南方医科大学学报2016，Vol.36Issue(6)：880-883,4.DOI:10.3969/j.issn.1673-4254.2016.06.26
肾移植术后肺部真菌感染的临床分析
Pulmonary fungal infection after renal transplantation:analysis of 40 cases
摘要
Abstract
Objective To explore the clinical characteristics, therapeutic measures and risk factors of pulmonary fungal infection in patients after renal transplantation. Methods The clinical data of 176 patients receiving renal allograft transplantation with postoperative infections were retrospectively analyzed. Among the patients, 40 were diagnosed to have pulmonary fungal infection, and their clinical symptoms, signs, radiographic findings, pathogenic bacterial culture, histopathological examination, and treatments were analyzed. Results The 40 recipients with postoperative pulmonary fungal infection included 25 male and 15 female patients with a mean age of 49 years. Twenty-eight of the patients developed pulmonary fungal infection within 6 months after transplantation. Positive pathogen cultivation was reported in 19 cases, and Candida albicans was detected in 11 cases, Candida krusei in 2 cases, Candida glabrata in 3 cases, Candida tropicalis in 1 case, aspergillosis in 1 case, and Candida mycoderma in 1 case. Twenty-four of out of the 40 cases were found to have co-infection. All the patients received antifungal drugs and adjuvant treatments, and 38 patients were cured and 2 died. Conclusion Pulmonary fungal infection often occurs within 6 months after renal transplantation. The most common fungal pathogen is Candida albicans, and the patients often had coinfections. Early diagnosis and timely intervention with antifungal drugs and comprehensive measures are critical in the management of pulmonary fungal infection following renal transplantation.关键词
肾移植/肺部真菌感染/危险因素Key words
renal transplantation/pulmonary fungal infection/risk factors引用本文复制引用
于立新,曾明星..肾移植术后肺部真菌感染的临床分析[J].南方医科大学学报,2016,36(6):880-883,4.基金项目
国家自然科学基金（81350009） Supported by National Natural Science Foundation of China (81350009) （81350009）
