中国耳鼻咽喉头颈外科2016，Vol.23Issue(2)：69-72,4.DOI:10.16066/j.1672-7002.2016.02.003
耳后注射甲泼尼龙琥珀酸钠联合常规药物治疗重度突发性聋
Efifcacy of combined postauricular methylprednisolone injection and systemic therapy for profound Idiopathic sudden hearing loss
贾弘光 1于湛 1黄小兵1
作者信息
- 1. 首都医科大学附属北京安贞医院耳鼻咽喉头颈外科，北京 100028
- 折叠
摘要
Abstract
[ABSTRACT]OBJECTIVETo investigate the efficacy and the related complications of combinedpostauricular methylprednisolone injection and systemic therapy for profound idiopathic sudden hearing loss (ISSNHL). METHODSTotal of 60 patients with ISSNHLwho had received therapy from June 2014 to May 2015 in Beijing Anzhen Hospital affiliated to Capital University of Medical Science,were randomly divided into 2 groups,the systemic application group (30 patients): dexamethasone (DEX) was applied intravenously in dose of 10 mg×5 d, and the postauricular injection group (30 patients): methylprednisolone sodium suecinate was injected subperiosteally near the upper one-thirds of postauricular sulcus every day, 40 mg×5 d.All 60 patients received the same medications for 2 weeks to improve the hearing. Hearing and tympanic membrane were monitered before the injections and two weeks after the termination of injections. SPSS 16.0 software was used to analyze the data.RESULTSThe postauricular injection group: 23 of 30 ears had improvement of hearing. No related complications were reported. The systemic application group: 23 of 31 ears had improvement of hearing (P>0.05) No related complications were reported.CONCLUSIONCombined postauricular methylprednisolone injection and systemic medications therapy can be considered as is an effective therapy for profound idiopathic sudden hearing loss. It can avoid the side-effects of high dose systemic corticostemid treatment. For ISSNHL patients, postauricular methylprednisolone injection may be an appropriate treatment.关键词
听觉丧失,突发性/糖皮质激素类/临床方案/耳后注射Key words
Hearig Loss, Sudden/Glucocorticoids/Clinical Protocols/postauricular injection引用本文复制引用
贾弘光,于湛,黄小兵..耳后注射甲泼尼龙琥珀酸钠联合常规药物治疗重度突发性聋[J].中国耳鼻咽喉头颈外科,2016,23(2):69-72,4.
