中国耳鼻咽喉头颈外科2016，Vol.23Issue(2)：106-110,5.DOI:10.16066/j.1672-7002.2016.02.012
变应性鼻炎患者伴发食物变应原致敏的特异性抗体检测分析
Detection and analysis of specific antibodies of food allergens in patients with allergic rhinitis
王俊阁 1陈钢 1俞琳琳 1李婉英 2盖建青 1闫新宇 1吴慧莉2
作者信息
- 1. 首都医科大学附属北京中医医院耳鼻咽喉科，北京100010
- 2. 煤炭总医院耳鼻咽喉科，北京100028
- 折叠
摘要
Abstract
[ABSTRACT]OBJECTIVETo investigate the relationship between food allergen specific IgE, IgG and allergic rhinitis, and to explore the significance of food allergen in the diagnosis and prevention of allergic rhinitis.METHODSTen kinds of food specific IgE were detected by Western blot and 14 kinds of food specific IgG were detected by ELISA in 2860 allergic rhinitis patients. The positive results of specific IgE and specific IgG were retrospectively analyzed.RESULTSThere was no difference in positive rate of allergen in patients with different gender. Total positive rate of food specific IgE was 68.5%. The specific IgE positive rate of crab was 31.5%, shrimp 27.6%, milk 21.3%, fish assemblages 19.2%, freshwater fish assemblages 18.3% and soybean 17.2%. With the growth of age, the specific IgE positive rate of peanut increased, but eggs decreased. The total positive rate of food allergen specific IgG was 81.5%. The specific IgG positive rate of egg was 59.4%, milk 38.2%, codfish 32.6%, soybean 22.8%, rice 19% and shrimp 12.7%. With the growth of age, the specific IgG positive rate of crab increased. Specific IgE and IgG of soybean, milk, crab, shrimp and fish were correlated well.CONCLUSIONThe detection of specific food allergen antibodies is helpful for the diagnosis of allergic rhinitis.关键词
变应原/食物过敏/鼻炎,变应性,常年性/变应原特异性IgE/变应原特异性IgGKey words
Allergens/Food Hypersensitivity/Rhinitis, Allergic, Perennial/specific IgE/specific IgG引用本文复制引用
王俊阁,陈钢,俞琳琳,李婉英,盖建青,闫新宇,吴慧莉..变应性鼻炎患者伴发食物变应原致敏的特异性抗体检测分析[J].中国耳鼻咽喉头颈外科,2016,23(2):106-110,5.
