中国耳鼻咽喉头颈外科2016，Vol.23Issue(5)：247-249,3.DOI:10.16066/j.1672-7002.2016.05.001
经静脉低剂量亚甲蓝甲状旁腺定位在甲状腺手术中的初步应用
Localization of parathyroid glands with intravenous low-dose methylene blue in thyroidectomy
钟琦 1房居高 1马泓智 2李平栋 1冯凌2
作者信息
- 1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科，耳鼻咽喉头颈科学教育部重点实验室 首都医科大学，北京 100730
- 2. 北京市头颈部分子病理重点实验室，北京 100005
- 折叠
摘要
Abstract
[ABSTRACT]OBJECTIVETo explore the efficacy and safety of localization for parathyroid glands with intravenous low dosage of methylene blue in thyroidectomy. METHODSWe retrospectively reviewed the clinical data of 41 patients who suffered from thyroid papillary carcinoma between Aug, 2014 and Jan, 2015 (9 males and 32 females, with a median age of 46 years). Thirty eight patients underwent primary thyroidectomy and 3 patients underwent second operation. A variety of thyroidectomy was performed in all patients, and who also underwent intravenous (3-4) mg/kg methylene blue in operation. RESULTSEighty four parathyroid glands were stained. Among 39 patients who's parathyroid glands were stained, the mean dyeing time was (31.27±9.41) min. Dyeing rates and dyeing time were not significantly different between 3 mg/kg group and 4 mg/kg group (t=0.24 and 0.20, all P>0.05). None of patients had the hypoparathyroidism problem such as peri-oral numbness, tingling, muscle aches and spasms. According to postoperative monitoring of parathyroid hormone, all of patients had no permanent hypofunction of the parathyroid gland. Neurotoxic effects and other serious side effects were not observed in all patients. CONCLUSIONIntravenous low-dose methylene blue in thyroidectomy is a safe, easy, and effective technique that facilitates rapid identification of parathyroid gland.关键词
亚甲蓝/甲状旁腺/外科手术/甲状腺肿瘤/甲状腺手术Key words
Methylene Blue/Parathyroid Glands/Surgical Procedures, Operative/Thyroid Neoplasms/thyroidectomy引用本文复制引用
钟琦,房居高,马泓智,李平栋,冯凌..经静脉低剂量亚甲蓝甲状旁腺定位在甲状腺手术中的初步应用[J].中国耳鼻咽喉头颈外科,2016,23(5):247-249,3.
