中国耳鼻咽喉头颈外科2016，Vol.23Issue(5)：273-274,2.DOI:10.16066/j.1672-7002.2016.05.009
慢性分泌性中耳炎中Th17相关细胞因子白介素-17的测定
Determination of Th17-related cytokine interleukin17 in patients of chronic otitis media with effusion
摘要
Abstract
OBJECTIVETo study the role of interleukin 17 (IL-17) in the pathogenesis of chronic otitis media with effusion (COME).METHODSThe expression of IL-17 in middle ear effusion (MEE) and blood plasma were measured in 30 patients (48 ears) by means of Cytometric Bead Array (CBA), as well as in 20 normal volunteers.RESULTSCompared with the control group, the level of IL-17 significantly increased in the peripheral blood of COME patients (P<0.05). What was more, the level of IL-17 in the MEE was higher than that in peripheral blood of COME patients (P<0.05).CONCLUSIONIL-17, as an important immunoregulatory mediator, may play an important role in chronic course of COME.关键词
中耳炎,伴渗出液/白细胞介素17/病理过程/流式微球分析法Key words
Otitis Media with Effusion/Interleukin-17/Pathologic Processes/cytometric bead array引用本文复制引用
秦彩虹,赵守琴,李洁,王阳,杨琳,任冉..慢性分泌性中耳炎中Th17相关细胞因子白介素-17的测定[J].中国耳鼻咽喉头颈外科,2016,23(5):273-274,2.基金项目
国家自然科学基金资助项目 （）
