口腔疾病防治2016，Vol.24Issue(6)：325-330,6.DOI:10.12016/j.issn.2096-1456.2016.06.002
EB病毒和牙龈卟啉单胞菌协同感染与妊娠期慢性牙周炎的相关性研究
Relationship between maternal chronic periodontitis and coinfection of Epstein-Barr virus and Porphyromonas gingivalis
摘要
Abstract
Objective To study the correlation between coinfection of Epstein⁃Barr virus (EBV) and Porphyromon⁃as gingivalis(Pg) and severity of maternal chronic periodontitis in pregnant women. Methods Saliva samples were collected from 36 pregnant women with chronic periodontitis and 36 pregnant women with healthy periodontal status. EBV was detected using nested polymerase chain reaction (PCR), Pg was detected using 16S rRNA based PCR. Clini⁃cal periodontal indices were recorded through periodontal examination. Correlation between the coinfection and severity of maternal chronic periodontitis were analyzed. Results The results showed no significant differences in prevalence of infection of EBV or Pg between pregnant women with chronic periodontitis and with healthy periodontal status (P>0.05). Contemporaneously, coinfection prevalence of EBV and Pg showed significant differences between two groups (P = 0.028). Coinfection of EBV and Pg showed significant association with bleeding on probing index (BOP) (P =0.003). No significant associations were found between the coinfection and periodontal depth(PD) or clinical attachment loss (CAL) (P>0.05). Conclusion Relationship between coinfection of EBV and Pg and maternal chronic periodonti⁃tis needs further investigation.关键词
妊娠期女性/慢性牙周炎/EB病毒/牙龈卟啉单胞菌/协同感染Key words
Pregnant women/Chronic periodontitis/Epstein-Barr virus/Porphyromonas gingivalis/Coinfection分类
医药卫生引用本文复制引用
祝策,陆海霞,李飞,冯希平..EB病毒和牙龈卟啉单胞菌协同感染与妊娠期慢性牙周炎的相关性研究[J].口腔疾病防治,2016,24(6):325-330,6.基金项目
国家自然科学基金青年项目（81400496）；高等学校博士学科点专项科研基金 （）
