口腔疾病防治2016，Vol.24Issue(6)：366-369,4.DOI:10.12016/j.issn.2096-1456.2016.06.011
米诺环素软膏与碘甘油辅助治疗第三磨牙冠周炎伴牙龈脓肿的效果比较
Comparative study on the clinical effect of minocycline hydrochloride ointment and lodine glycerin as adju-vant therapy for pericoronitis with parulis
摘要
Abstract
Objective To compare the clinical effects of minocycline hydrochloride ointment (Periocline) and lo⁃dine glycerin as adjuvant therapy for pericoronitis with parulis. Methods 164 college students suffering from pericoro⁃nitis with parulis were divided into 2 groups randomly: observation group (82 cases) and control group (82 cases). All cases were treated with incision and drainage of the parulis, and then pericoronal rinsing. What's more, tinidazole and cefradine plus compound borax gargle mouthwash were given to them. 2% Periocline was filled into the periodontal pocket for the observation group (q3d) while 1% lodine glycerin was filled into the periodontal pocket for the control group (qd). Clinical effects of the two groups were observed and compared 3 days later. Results The effective rate of observation group (93.9%) was higher than that of control group (78.0%) with statistically significance (χ2=8.546, P=0.003). No drug adverse reaction occured. Conclusion It shows good effects when Periocline is applied as an adju⁃vant therapy for pericoronitis with parulis.关键词
第三磨牙/冠周炎/米诺环素/碘甘油/缓释药Key words
The third molar/Pericoronitis/Minocycline/Lodine glycerin/Release drug分类
医药卫生引用本文复制引用
葛光华,李晋芳,江小平,吴琼..米诺环素软膏与碘甘油辅助治疗第三磨牙冠周炎伴牙龈脓肿的效果比较[J].口腔疾病防治,2016,24(6):366-369,4.基金项目
国家自然科学基金（61300106）；广东省医学科学技术研究基金 （）
