解放军医药杂志2016，Vol.28Issue(5)：83-86,4.DOI:10.3969/j.issn.2095-140X.2016.05.020
严重创伤失血患者大量输血后血糖水平、多器官功能障碍综合征发生率和病死率的观察
Clinical Observation of Blood Glucose Level,MODS Incidence and Fatality Rates of Severe Trauma and Hemor-rhage Patients after Massive Transfusion
摘要
Abstract
Objective To investigate the effects on blood glucose level,incidence and fatality rates of multiple organ dysfunction syndrome(MODS)in severe trauma and hemorrhage patients after massive transfusion in order to pro-vide evidence of effective transfusion. Methods Clinical data of 391 severe trauma and hemorrhage patients after blood transfusion during December 2012 and December 2015 was retrospectively analyzed. The patients were divided into mas-sive transfusion group(adult infusion of red cell suspension≥20. 0 U or 0. 3 U / kg body weight within 24 h,n = 156) and moderate transfusion group(blood transfusion volume ﹤ massive transfusion standard within 24 h,n = 235). Glucose levels before the blood transfusion(GLU0 ),and glucose levels 3 d after the blood transfusion(GLU3 ),GLU3 / GLU0 val-ues and incidence and fatality rates of MODS were observed and evaluated in the two groups. Results The values of GLU3 ,GLU3 / GLU0 and incidence rate of MODS in massive transfusion group were significantly higher than those in mod-erate transfusion group(P ﹤ 0. 01). There was no significant difference in fatality rate in the two groups( P ﹥ 0. 05). Conclusion The massive transfusion can not effectively decrease the incidence and fatality rates of MODS in severe trau-ma and hemorrhage patients,on the contrary,massive transfusion can induce MODS and increase fatality rate by promo-ting stress level of blood glucose.关键词
创伤和损伤/大量输血/血糖/多器官功能障碍综合征/病死率Key words
Wounds and injuries/Massive transfusion/Blood glucose/Multiple organ dysfunction syndrome/Fatality rate分类
医药卫生引用本文复制引用
戴蕴,王占科,乐爱平,黄强,王长奇,王庆莅..严重创伤失血患者大量输血后血糖水平、多器官功能障碍综合征发生率和病死率的观察[J].解放军医药杂志,2016,28(5):83-86,4.基金项目
江西省科技支撑重点项目（2008BAI52B03）；江西省卫生厅课题 （）
