河北医学2016，Vol.22Issue(5)：740-742,3.DOI:10.3969/j.issn.1006-6233.2016.05.014
二甲双胍治疗2型糖尿病与亚临床甲状腺功能减退症关系的研究
Research on Relationship between Metformin Treating II Diabetes Mellitus and Subclinical Hypothyroidism
摘要
Abstract
Objective:To explore the relationship between metformin in treating II diabetes mellitus and subclinical hypothyroidism. Methods: 124 cases with II diabetes mellitus treated in our hospital from June 2013 to July 2014 were selected and divided into two groups randomly, the control group and the observation group, each group with 62 cases. The control group was treated with bayer pharma, and the observation group was treated with metformin. The subclinical hypothyroidism of two groups was observed after treatment. Re-sults:The experimental results indicated that TSH and HOMA-IR of the observation group was evidently lower than that of the control group ( P<0.05) , and the other indicators had no evident difference( P>0.05) . Apply-ing metformin was a protective factor of reducing subclinical hypothyroidism, and sex is an dangerous factor. Conclusion:Applying metformin to treat II diabetes mellitus can reduce the incidence rate of subclinical hy-pothyroidism, which is worthy of promotion and application.关键词
2型糖尿病/甲状腺功能减退症/二甲双胍Key words
II diabetes mellitus/Hypothyroidism/Metformin引用本文复制引用
马玉霞,牟建军..二甲双胍治疗2型糖尿病与亚临床甲状腺功能减退症关系的研究[J].河北医学,2016,22(5):740-742,3.基金项目
陕西省卫生厅科学研究基金项目，(编号:2012B2) （编号:2012B2）
