河北医学2016，Vol.22Issue(5)：742-744,745,4.DOI:10.3969/j.issn.1006-6233.2016.05.015
少腹逐瘀汤联合康妇消炎栓治疗急性盆腔炎临床疗效及对血清炎性因子的影响
Clinical Efficacy of Shaofu Zhuyu Tang Combined with Kangfu Anti-inflammatory Suppository in Treatment of Acute Pelvic Inflammatory Disease and the Effects on Serum Inflammatory Factors
摘要
Abstract
Objective:To investigate the clinical efficacy of Shaofu Zhuyu Tang combined with Kangfu anti-inflammatory suppository in treatment of acute pelvic inflammatory disease, and to lighten the inflammato-ry reaction of the body. Methods:A total of 78 eligible patients were selected and randomly divided into ob-servation group and control group, with 40 patients in the observation group and 38 patients in the control group. All the patients were routinely treated with antibiotics, but the patients of the observation group were given with Shaofu Zhuyu Tang and Kangfu anti-inflammatory suppository additionally, and the clinical effica-cies and changes in serum TNF-α, IL-1β, IL-8 and CRP levels were compared between the two groups. Re-sults:Before the therapies, the patients of the two groups had similar serum TNF-α, IL-1β, IL-8 and CRP levels, and the differences were statistically insignificant ( P>0.05) . At the end of course of treatment, the pa-tients of both groups had decreased serum TNF-α, IL-1β, IL-8 and CRP levels when compared with those before the therapies, but the patients of the observation group had greater decreasing extents than the control group, and the differences were statistically significant ( P<0.05) . Of the observation group, 20 patients were cured, 10 patients were responsive to the therapy excellently, 7 patients were responsive to the therapy, and 3 patients were unresponsive to the therapy;the total effective rate was 92.50%. While of the control group, 12 patients were cured, 9 patients were responsive to the therapy excellently, 6 patients were responsive to the therapy, and 11 patients were unresponsive to the therapy;the total effective rate was 71.05%;the difference was statistically significant ( P<0.05) . Conclusion:Based on routine use of antibiotics, additional use of Sha-ofuzhuyu tang and Kangfu anti-inflammatory suppository can effectively lighten the inflammatory reaction, ele-vate clinical efficacy, and improve the prognosis in patients with acute pelvic inflammatory disease.关键词
急性盆腔炎/炎症因子/少腹逐瘀汤/康妇消炎栓/替硝唑Key words
Acute pelvic inflammatory disease/Inflammatory factor/Shaofu Zhuyu Tang/Kangfu anti-inflammatory suppository/Tinidazole引用本文复制引用
王青慧,高霞,陈玉..少腹逐瘀汤联合康妇消炎栓治疗急性盆腔炎临床疗效及对血清炎性因子的影响[J].河北医学,2016,22(5):742-744,745,4.基金项目
中国高校医学期刊临床专项资金项目，(编号:NO11221407) （编号:NO11221407）
