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人工肝联合凉血解毒化瘀方治疗重型乙肝疗效观察

李守娟 王丽 胡朝霞 王磊 吴蓓 段萌 朱丽 李筠

湖南中医药大学学报2016,Vol.36Issue(6):20-23,4.
湖南中医药大学学报2016,Vol.36Issue(6):20-23,4.DOI:10.3969/j.issn.1674-070X.2016.06.006

人工肝联合凉血解毒化瘀方治疗重型乙肝疗效观察

Clinical Observation of Artificial Liver Combined with Liangxue Jiedu Huayu Fang on Treatment of Severe Hepatitis B

李守娟 1王丽 1胡朝霞 1王磊 1吴蓓 1段萌 1朱丽 1李筠2

作者信息

  • 1. 四川省成都市公共卫生临床医疗中心,四川 成都 610066
  • 2. 中国人民解放军第302医院,北京 100039
  • 折叠

摘要

Abstract

Objective To evaluate of artificial liver support system combined with TCM Liangxue Jiedu Huayu Fang on chronic severe hepatitis B. Methods According to the different patterns of patients using in our hospital to carry out artificial liver support system (plasma perfusion plasmapheresis, joint plasma exchange, double plasma bilirubin adsorption joint plasma exchange adsorption, molecular adsorption recycling) combined with Liangxue Jiedu Huayu Fang to treat 46 cases of chronic severe hepatitis B, and another 30 patients as control group were treated with basic therapy add artificial liver support system. Results After treatment, the clinical symptoms, liver function, prothrombin activity (PTA), blood ammonia of two groups were obviously improved, the treatment group was significantly better than the control group (P<0.05). The result of 46 patients in the treatment group was as follow: cured effect in 9 cases, obvious effect in 25 cases, effect in 6 cases, no effect in 3 cases, died in 3 cases, and the total efficiency was 86.96%, which is better than the control group. After following up for half a year, the survival rate was higher than the control group (P<0.05). Conclusion Artificial liver support system is an effective method for the treatment of chronic severe hepatitis B, which combined with Liangxue Jiedu Huayu Fang can improve the clinical curative effect, and reduce the mortality of patient.

关键词

人工肝支持系统/重型乙肝/中西医结合治疗/凉血解毒化瘀方

Key words

artificial liver support system/severe hepatitis B/combined treatment of TCM and Western medicine/Liangxue Jiedu Huayu Fang

分类

医药卫生

引用本文复制引用

李守娟,王丽,胡朝霞,王磊,吴蓓,段萌,朱丽,李筠..人工肝联合凉血解毒化瘀方治疗重型乙肝疗效观察[J].湖南中医药大学学报,2016,36(6):20-23,4.

基金项目

国家科技重大专项“艾滋病和病毒性肝炎”等重大传染病防治(2012ZX10005-005)。 (2012ZX10005-005)

湖南中医药大学学报

OACSTPCD

1674-070X

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