湖南中医药大学学报2016，Vol.36Issue(6)：56-59,4.DOI:10.3969/j.issn.1674-070X.2016.06.014
无糖型半夏泻心颗粒制备工艺的研究
Study on Preparation Technology of Sugar-Free Banxia Xiexin Granules
李丹丹 1杨玲玲 2奉建芳 2唐志书3
作者信息
- 1. 陕西中医药大学，陕西 咸阳 712046
- 2. 南京朗尼医药科技有限公司，江苏 南京 210169
- 3. 桂林医学院，广西 桂林 541004
- 折叠
摘要
Abstract
Objectve To optimize preparation technology of sugar-free banxia Xiexin granules. Methods Using the content of Baicalin, berberine, and the extract yield as indexes, L9(34) orthogonal design and multi-index grading method was used to optimize the extraction process with water of sugar-free Banxia Xiexin granules. granules formability and pelletization as indexes, the types and combination ratio of accessories and corrigent were investigated. Results The best optimum extraction technology was as follows: Coptis Chinensis was extracted with 70% ethanol, residue and the other six kinds of herbs in the prescription was extracted for three times: 9 times water for 2.5 h at the first time, 8 times water for 1 h at the second time, 6 times water for 0.5 h at the third time. The optimal ratio of extraction-dextrine-soluble starch-sweeteners was 1∶0.6∶0.2∶0.015, the wetting agent was 85% ethanol. Conclusion The process is reasonable and feasible, and it is suitable for the preparation process of sugar-free Banxia Xiexin granules.关键词
无糖型半夏泻心颗粒/正交实验/制备工艺Key words
sugar-free Banxia Xiexin granules/orthogonal experiment/preparation technology分类
医药卫生引用本文复制引用
李丹丹,杨玲玲,奉建芳,唐志书..无糖型半夏泻心颗粒制备工艺的研究[J].湖南中医药大学学报,2016,36(6):56-59,4.
