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咽炎清滴丸对急性咽炎大鼠模型抗炎机理研究

刘雪艳 毛志刚 王平 高雁 张华芸

药学研究2016,Vol.35Issue(6):319-321,3.
药学研究2016,Vol.35Issue(6):319-321,3.DOI:10.13506/j.cnki.jpr.2016.06.003

咽炎清滴丸对急性咽炎大鼠模型抗炎机理研究

Experimental study on effect of Yanyanqing Dropping Pill in acute pharyngitis model rats

刘雪艳 1毛志刚 2王平 3高雁 2张华芸1

作者信息

  • 1. 烟台毓璜顶医院,山东 烟台 264000
  • 2. 烟台东诚大洋制药有限公司,山东 烟台 265500
  • 3. 山东省中医药研究院,山东 济南 250014
  • 折叠

摘要

Abstract

Objective To investigate the anti -inflammatory action of Yanyanqing Dropping Pill and the expression of IL -1 β,IL -6,TNF -αin acute pharyngitis model rats.Methods Ear swelling model in mice induced by xylene and foot swelling model in rats induced by albumen were chosen to investigate the anti -inflammatory action of Yanyanqing Dropping Pill;Acute pharyngitis model rats induced by 1 5% ammonia were administrated with Yanyanqing Dropping Pill to investi-gate the change of the contents of IL -1 β,IL -6,TNF -α.Results Yanyanqing Dropping Pill can significantly against the mouse ear swelling caused by dimethylbenzene,can significantly inhibit the toes swelling of rats caused by formaldehyde, and change of the contents of IL -1 β,IL -6,TNF -αin acute pharyngitis model rats.Conclusion Yanyanqing Dropping Pill displayed significant effects on acute pharyngitis model rats.

关键词

咽炎清滴丸/急性咽炎/白细胞介素-1β/白细胞介素-6/肿瘤坏死因子-α

Key words

Yanyanqing Dropping Pill/Acute pharyngitis/IL -1 β/IL -6/TNF -α

分类

医药卫生

引用本文复制引用

刘雪艳,毛志刚,王平,高雁,张华芸..咽炎清滴丸对急性咽炎大鼠模型抗炎机理研究[J].药学研究,2016,35(6):319-321,3.

药学研究

2095-5375

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