药学研究2016，Vol.35Issue(6)：322-324,327,4.DOI:10.13506/j.cnki.jpr.2016.06.004
制川乌与瓜蒌不同比例配伍前后生物碱成分分析
The content changes of alkaloids in Aconiti Cocta Radix before and after the combination with Trichosanthes Fructus in different ratios
许利婷 1张楠 1卢海迪 1翁丽丽 1王淑敏1
作者信息
- 1. 长春中医药大学药学院，吉林 长春 130117
- 折叠
摘要
Abstract
Objective To study the changing tendency of alkaloids in Aconiti Cocta Radix combined with Trichosanthes Fructus in different ratios,provide the scientific of incompatibility while elaborate the material basis of compatibility.Meth-ods HPLC was adopted to analyze the content changes of alkaloids in different ratios of compatibility of Aconiti Cocta Ra-dix.Results The change of quantities of chemical composition was obvious before and after compatibility.When Snakeg-ourd Fruit weight was within a certain range,single ester type alkaloid decreased with increment of Snakegourd Fruit ratio;Single ester type alkaloid content had a rising trend when Snakegourd Fruit weight increased to a certain amount.Double es-ter alkaloid content decreased with the increment of Snakegourd Fruit ratio.Conclusion After the compatibility of Aconiti Cocta Radix combined with Trichosanthes Fructus,benzoyl class alkaloid content first reduced with the increase of Snakeg-ourd Fruit weight and had increasing trend when Snakegourd Fruit weight continued to increase;Aconitum class alkaloid content reduced with the increase of Snakegourd Fruit weight which contradicts the traditional Chinese medicine "Eighteen Incompatible Medicaments"description indicating compatibility of Trichosanthes Fructus and Aconiti Cocta Radix was com-patible,or even if it was incompatible,was not caused by aconitum class alkaloid.关键词
制川乌/瓜蒌/配伍/高效液相色谱法Key words
Aconiti Cocta Radix/Trichosanthes Fructus/Compatibility/HPLC分类
医药卫生引用本文复制引用
许利婷,张楠,卢海迪,翁丽丽,王淑敏..制川乌与瓜蒌不同比例配伍前后生物碱成分分析[J].药学研究,2016,35(6):322-324,327,4.
