色谱2016，Vol.34Issue(6)：596-601,6.DOI:10.3724/SP.J.1123.2016.03019
萃取纳升喷雾-离子迁移谱法现场快速筛查化妆品中8种禁用抗生素
Rapid on-site screening of eight prohibited antibiotics in cosmetics using extraction nano-electrospray coupled with ion mobility spectrometry
摘要
Abstract
A rapid on-site method has been developed for the identification of eight prohibited antibiotics in cosmetics using extraction nano-electrospray coupled with ion mobility spectrom-etry. The experimental conditions for capillary pulling,extraction nano-electrospray,and ion mobility spectrometry were investigated and optimized. Under the optimum conditions,the lim-its of detection( LODs)for the eight prohibited antibiotics were 20 mg/kg. The instrumental analysis time for a single ion mobility spectrometry run was less than 20 ms,and the total peri-od for sample analysis was less than 30 s. The suspicious positive samples were subjected to further verification by ultra-performance liquid chromatography-tandem mass spectrometry ( UPLC-MS/MS). The proposed method is rapid,efficient with greatly simplified work flows and can provide potential analytical possibility for outside-the-lab screening of cosmetics for the presence of illicit ingredients.关键词
萃取纳升喷雾/离子迁移谱/禁用抗生素/化妆品/现场快速筛查Key words
extraction nano-electrospray/ion mobility spectrometry( IMS)/prohibited antibi-otics/cosmetics/rapid on-site screening分类
化学化工引用本文复制引用
孟宪双,马强,马龙华,陈丽华,韩超,白桦,吴青..萃取纳升喷雾-离子迁移谱法现场快速筛查化妆品中8种禁用抗生素[J].色谱,2016,34(6):596-601,6.基金项目
国家质检总局科技计划项目（2015IK314）；中央级公益性科研院所基本科研业务费专项资金资助项目（2016JK004）． Foundation itemScience Research Program of General Administration of Quality Supervision，Inspection and Quarantine of China（ No．2015IK314）；Basic Research Fund for Central Public Interest Institutes（ No．2016JK004）． （）
