中国组织工程研究2016，Vol.20Issue(25)：3659-3664,6.DOI:10.3969/j.issn.2095-4344.2016.25.002
Modified kugel补片疝环充填式无张力疝修补的生物相容性
Biocompatibility of modified Kugel mesh in mesh plug tension-free hernioplasty
王庆广 1王燕红 2张彩坤 3张豪英 3孔繁忠1
作者信息
- 1. 淄博市第一医院，普外科，山东省淄博市 255200
- 2. 淄博市第一医院，儿童保健科，山东省淄博市 255200
- 3. 山东中医药高等专科学校临床教研室，山东省烟台市 264100
- 折叠
摘要
Abstract
BACKGROUND: Mesh plug tension-free hernioplasty is commonly used for inguinal hernia. In the operation, different mesh materials can be selected, among which the modified Kugel mesh is extensively applied. OBJECTIVE: To observe the biocompatibility of modified Kugel mesh in mesh plug tension-free hernioplasty for inguinal hernia. METHODS: Total y 79 cases of inguinal hernia were treated by mesh plug tension-free hernioplasty. The patients were randomly divided into observation group repaired with Bard mesh (modified Kuge) (n=38) and control group repaired with Prolene mesh (n=41). After 12-month fol ow-up, levels of interleukin 6, C-reactive protein and tumor necrosis factor α were detected and compared before and after treatment;adverse events, including wound infection or infection caused by the mesh in the two groups were recorded. RESULTS AND CONCLUSION: Levels of interleukin 6, C-reactive protein and tumor necrosis factor α in the two groups were significantly decreased after treatment than before treatment (P < 0.05). No wound infection or infection caused by the mesh appeared in both two groups. Although scrotum effusion occurred in two cases of each group, their outcomes al improved significantly after active puncture and suction treatment without other serious problems. No recurrence was found during the 12-month fol ow-up. These results show that the modified Kugel mesh has good biocompatibility in mesh plug tension-free hernioplasty for inguinal hernia.关键词
生物材料/材料相容性/膜生物材料/疝/腹股沟疝/无张力/外科手术/疝修补术/补片/疝环充填式/生物相容性/炎性因子分类
医药卫生引用本文复制引用
王庆广,王燕红,张彩坤,张豪英,孔繁忠..Modified kugel补片疝环充填式无张力疝修补的生物相容性[J].中国组织工程研究,2016,20(25):3659-3664,6.
