中国肺癌杂志2016,Vol.19Issue(6):394-398,5.DOI:10.3779/j.issn.1009-3419.2016.06.19
液体活检及其在非小细胞肺癌诊治中的研究进展
Advances in Liquid Biopsy and its Clinical Application in the Diagnosis and Treatment of Non-small Cell Lung Cancer
摘要
Abstract
With the advances of technology, great progresses have been made in liquid biopsy in recent years. Liquid biopsy is currently playing a more and more important role in early diagnosis and treatment of cancer. Compared with traditional tissue biopsy, liquid biopsy is more popular in clinical practice due to its non-invasiveness, convenience and high repeatability. It has huge potential in the future. hTis review introduces circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) as the most important objects in liquid biopsy, mainly focusing on their history, biological characteristics, de-tection technologies, limitations and applications in non-small cell lung cancer.关键词
液体活检/循环肿瘤细胞/循环肿瘤DNA/肺肿瘤Key words
Liquid biopsy/Circulating tumor cells/Circulating tumor DNA/Lung neoplasms引用本文复制引用
郑迪凡,陈海泉..液体活检及其在非小细胞肺癌诊治中的研究进展[J].中国肺癌杂志,2016,19(6):394-398,5.基金项目
本文受国家自然科学基金项目(No.81330056和No.81572253)资助 ()