中国内镜杂志2016，Vol.22Issue(6)：72-77,6.DOI:10.3969/j.issn.1007-1989.2016.06.018
间苯三酚与米索前列醇在宫腔镜术前促宫颈成熟效果比较的Meta分析
Phloroglucinol and Misoprostol for cervix pretreatment before diagnostic hysteroscopy:a meta-analysis of randomized controlled trials
孙景丽 1王青 2高绍凤 1赵颖 1李颖 1王秀侠 1王英俊3
作者信息
- 1. 山东省单县中心医院 妇产科，山东 单县 274300
- 2. 浙江省义乌市妇幼保健院 妇产科，浙江 义乌322000
- 3. 浙江大学医学院附属妇产科医院 妇产科，浙江 杭州 310000
- 折叠
摘要
Abstract
Objective To determine the efficiency and safety of Phloroglucinol and Misoprostol for cervix pretreat-ment before diagnostic hysteroscopy. Methods Trials were located through electronic searches of the PubMed, MED-LINE, Springer, CNKI, VIP, CBM, WanFang Data (from the date of establishment of the databases to June 2015). Bibliographies of the retrieved articles were also checked. Result A total of 18 trials involving 2 341 patients were included. The Meta-analysis showed: application of Phloroglucinol lenovo better open and dilate the cervix [OȒ =2.95, 95 % CI (1.96, 4.45), = 0.000]; To better clarity of the operative field [ OȒ = 9.50, 95 % CI (6.46, 13.98), = 0.000]; To better shorten the operation time [OȒ =-4.12, 95 % CI (-5.75,-2.49), =0.000];To bet-ter able to reduce the amount of intraoperative leakage [ OȒ =0.22, 95%CI (0.10, 0.49), = 0.0002]; and postop-erative adverse reactions should be significantly lower than Misoprostol [ OȒ = 0.01, 95 % CI (0.00, 0.04), =0.000]. The difference was statistically significant. Conclusions Phloroglucinol is more effective and safer than Miso-prostol in inducing proper cervical priming and may be the optimal choice for cervical pretreatment before diagnostic hysteroscopy.关键词
间苯三酚/米索前列醇/宫腔镜检查/随机对照试验/Meta分析Key words
Phloroglucinol/Misoprostol/hysteroscope/randomized controlled trials/meta-analysis分类
医药卫生引用本文复制引用
孙景丽,王青,高绍凤,赵颖,李颖,王秀侠,王英俊..间苯三酚与米索前列醇在宫腔镜术前促宫颈成熟效果比较的Meta分析[J].中国内镜杂志,2016,22(6):72-77,6.
