紫杉醇与5-氟尿嘧啶分别联合奈达铂治疗晚期鼻咽癌的临床观察OA北大核心CSTPCD
Clinical Observation of Paclitaxel or 5-Fluorouracil Combined with Nadaplatin in the Treatment of Ad-vanced Nasopharyngeal Carcinoma
目的：观察紫杉醇与5-氟尿嘧啶分别联合奈达铂治疗晚期鼻咽癌（NPC）的临床疗效及安全性。方法：将42例晚期NPC患者按随机数字表法分为观察组和对照组，各21例。两组患者均同步进行放疗。与此同时，观察组患者化疗方案为紫杉醇135 mg/m2，d1，联合奈达铂80 mg/m2，d2～4；对照组患者化疗方案为5-氟尿嘧啶500 mg/m2，d1～5，联合奈达铂80 mg/m2，d1～3。3周为1个疗程，两组患者均治疗2个疗程。观察两组患者临床疗效、生存…查看全部>>
OBJECTIVE:To observe clinical efficacy and safety of paclitaxel or 5-fluorouracil combined with nadaplatin in the treatment of advanced nasopharyngeal carcinoma(NPC). METHODS:42 patients with advanced NPC were randomly divided into observation group and control group(n=21). 2 groups of patients were treated with radiotherapy. Observation group received che-motherapy of paclitaxel(135 mg/m2,d1)and nedaplatin(80 mg/m2,d 2-4);control group received chemotherapy…查看全部>>
杨广胜;陈林;李玉
连云港市第一人民医院药学部，江苏连云港 222002连云港市第一人民医院耳鼻咽喉科，江苏连云港 222002连云港市第一人民医院肿瘤科，江苏连云港 222002
医药卫生
晚期鼻咽癌奈达铂紫杉醇5-氟尿嘧啶
Advanced nasopharyngeal carcinomaNedaplatinPaclitaxel5-fluorouracil
《中国药房》 2016 (17)
2397-2399,3
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